Se-Methylselenocysteine, also known as MSeC and SeMCys, is a drug potentially for the treatment of solid tumours. Se-methylselenocysteine offers selective protection against organ-specific toxicity induced by clinically active agents and enhances further antitumour activity, resulting in improved therapeutic index. Se-methylselenocysteine exerts pro-apoptosis effects through increasing Cx43 expression, which in turn down-regulates Bcl-2 and up-regulates bad expression.
MedKoo Cat#: 463885
Name: Se-Methylselenocysteine HCl
CAS#: 863394-07-4 (HCl)
Chemical Formula: C4H10ClNO2Se
Exact Mass: 218.9565
Molecular Weight: 218.54
Elemental Analysis: C, 21.98; H, 4.61; Cl, 16.22; N, 6.41; O, 14.64; Se, 36.13
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMF | 1.0 | 4.58 | |
| DMSO | 1.0 | 4.58 | |
| PBS (pH 7.2) | 10.0 | 45.76 |
The following data is based on the product molecular weight 218.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
