MedKoo Cat#: 413046 | Name: Azolimine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azolimine is the antagonized effect of mineralcorticoid on renal electrolyte excretion.

Chemical Structure

Azolimine
CAS#40828-45-3

Theoretical Analysis

MedKoo Cat#: 413046

Name: Azolimine

CAS#: 40828-45-3

Chemical Formula: C10H11N3O

Exact Mass: 189.0902

Molecular Weight: 189.22

Elemental Analysis: C, 63.48; H, 5.86; N, 22.21; O, 8.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Azolimine; CL90,748; CL-90,748; CL 90,748
IUPAC/Chemical Name
2-Imino-3-methyl-1-phenyl-4-imidazolidinone
InChi Key
KPMDCTAAOGEIKO-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H11N3O/c1-12-9(14)7-13(10(12)11)8-5-3-2-4-6-8/h2-6,11H,7H2,1H3
SMILES Code
O=C(CN1C2=CC=CC=C2)N(C)C1=N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 189.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gussin RZ, Ronsberg MA, Stokey EH, Cummings JR. Azolimine: a nonsteroidal antagonist of the effects of mineralocorticoids on renal electrolyte excretion. J Pharmacol Exp Ther. 1975 Oct;195(1):8-15. PMID: 1181406. 2: Treweeke NR, Hitchcock PB, Pardoe DA, Caddick S. Controlling diastereoselectivity in the reactions of enantiomerically pure alpha-bromoacyl- imidazolidinones with nitrogen nucleophiles: substitution reactions with retention or inversion of configuration. Chem Commun (Camb). 2005 Apr 14;(14):1868-70. doi: 10.1039/b417954d. Epub 2005 Feb 8. PMID: 15795770.