Afimetoran, also known as BMS 986256, is an Oral Novel Toll-like Receptor 7 and 8 (TLR7/8) Inhibitor. BMS-986256 has demonstrated efficacy in animal models of lupus as well as favorable PK and acceptable safety profiles in healthy subjects.
MedKoo Cat#: 575792
Name: Afimetoran
CAS#: 2171019-55-7
Chemical Formula: C26H32N6O
Exact Mass: 444.2638
Molecular Weight: 444.58
Elemental Analysis: C, 70.24; H, 7.26; N, 18.90; O, 3.60
The following data is based on the product molecular weight 444.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
