G-33378 | CAS# 1174-98-7 | Metabolite

MedKoo Cat#: 575749 | Name: G-33378

Description:

WARNING: This product is for research use only, not for human or veterinary use.

G-33378 is a metabolite of sulfinpyrazone that inhibits human platelet cyclo-oxygenase activity.

Chemical Structure

G-33378

CAS#1174-98-7

Theoretical Analysis

MedKoo Cat#: 575749

Name: G-33378

CAS#: 1174-98-7

Chemical Formula: C23H20N2O3S

Exact Mass: 404.1195

Molecular Weight: 404.48

Elemental Analysis: C, 68.30; H, 4.98; N, 6.93; O, 11.87; S, 7.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

G 33378; G33378; G-33378

IUPAC/Chemical Name

3,5-Pyrazolidinedione, 1-(4-hydroxyphenyl)-2-phenyl-4-(2-(phenylthio)ethyl)-

InChi Key

ZINXZZBZWUOJNZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C23H20N2O3S/c26-19-13-11-18(12-14-19)25-23(28)21(15-16-29-20-9-5-2-6-10-20)22(27)24(25)17-7-3-1-4-8-17/h1-14,21,26H,15-16H2

SMILES Code

Oc1ccc(cc1)N2N(C(=O)C(CCSc3ccccc3)C2=O)c4ccccc4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 404.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Del Maschio A, Livio M, Cerletti C, De Gaetano G. Inhibition of human platelet cyclo-oxygenase activity by sulfinpyrazone and three of its metabolites. Eur J Pharmacol. 1984 Jun 1;101(3-4):209-14. doi: 10.1016/0014-2999(84)90158-4. PMID: 6432556.