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MedKoo Cat#: 413003 | Name: CL 259763

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CL 259763 is an orally active compound capable of modifying the reactivity of certain lymphoid cell populations affected by the growth of a tumor.

Chemical Structure

CL 259763
CL 259763
CAS#734-22-5

Theoretical Analysis

MedKoo Cat#: 413003

Name: CL 259763

CAS#: 734-22-5

Chemical Formula: C14H12FNO3S

Exact Mass: 293.0522

Molecular Weight: 293.31

Elemental Analysis: C, 57.33; H, 4.12; F, 6.48; N, 4.78; O, 16.36; S, 10.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CL 259763; CL259763; CL-259763
IUPAC/Chemical Name
Acetamide, N-(4-((4-fluorophenyl)sulfonyl)phenyl)-
InChi Key
CHZUOCHJHAJYNO-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H12FNO3S/c1-10(17)16-12-4-8-14(9-5-12)20(18,19)13-6-2-11(15)3-7-13/h2-9H,1H3,(H,16,17)
SMILES Code
CC(NC1=CC=C(S(=O)(C2=CC=C(F)C=C2)=O)C=C1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 293.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wang BS, Lumanglas AL, James JP, Kelley KA, Silva J, Ruszala-Mallon V, Lin YI, Durr FE. Reconstitution of cytolytic alloreactivity with N-[4-[(4-fluorophenyl) sulfonyl]phenyl]acetamide (CL 259,763) in animals immunocompromised by cyclophosphamide. Int J Immunopharmacol. 1989;11(5):479-86. doi: 10.1016/0192-0561(89)90177-x. PMID: 2530180. 2: Wang BS, Ruszala-Mallon V, Wallace RE, Citarella RV, Lin YI, Durr FE. Modulation of the immune response to tumors by a novel synthetic compound, N-[4-[(4-fluorophenyl)sulfonyl]phenyl] acetamide (CL 259,763). Cancer Immunol Immunother. 1986;22(1):8-14. doi: 10.1007/BF00205710. PMID: 2939949. 3: Wang BS, Lumanglas AL, Lin YI, Durr FE. Generation of tumoricidal effector cells with a novel potentiator: N-[4-[(4-fluorophenyl)sulfonyl]phenyl] acetamide (CL 259,763). Int J Immunopharmacol. 1990;12(3):307-14. doi: 10.1016/0192-0561(90)90086-3. PMID: 2329020. 4: Wang BS, Ruszala-Mallon VM, Lumanglas AL, Silva J, Durr FE. Restoration of cytolytic T-lymphocyte response with a new immunopotentiator, N-(4-[(4-fluorophenyl)sulfonyl]phenyl)acetamide (CL 259, 763), in mice. Cancer Res. 1988 Apr 15;48(8):2135-7. PMID: 3258185.