NFAT:AP-1 inhibitor-10 is a novel inhibitor of the NFAT:AP-1:DNA interaction on the ARRE-2 element, binding to DNA in a sequence-selective manner and inhibiting the transcription of the Il2 gene and several other cyclosporin A-sensitive cytokine genes important for the effector immune response.
MedKoo Cat#: 463835
Name: NFAT:AP-1 inhibitor-10
CAS#: 841210-82-0
Chemical Formula: C22H19N5O2S
Exact Mass: 417.1259
Molecular Weight: 417.49
Elemental Analysis: C, 63.29; H, 4.59; N, 16.78; O, 7.66; S, 7.68
The following data is based on the product molecular weight 417.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
-2536.jpg "Mesocorydaline, (-)-")
