MedKoo Cat#: 575688 | Name: FR-7534

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FR-7534 is a calcium antagonist structurally similar to nifedipine.

Chemical Structure

FR-7534
FR-7534
CAS#62760-70-7

Theoretical Analysis

MedKoo Cat#: 575688

Name: FR-7534

CAS#: 62760-70-7

Chemical Formula: C19H22N2O7

Exact Mass: 390.1427

Molecular Weight: 390.39

Elemental Analysis: C, 58.46; H, 5.68; N, 7.18; O, 28.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
FR 7534; FR7534; FR-7534
IUPAC/Chemical Name
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-(hydroxymethyl)-6-methyl-4-(3-nitrophenyl)-, diethyl ester
InChi Key
LWTWJBUKUVHABE-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H22N2O7/c1-4-27-18(23)15-11(3)20-14(10-22)17(19(24)28-5-2)16(15)12-7-6-8-13(9-12)21(25)26/h6-9,16,20,22H,4-5,10H2,1-3H3
SMILES Code
CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCC)CO
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 390.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Meils CM, Gross GJ, Brooks HL, Warltier DC. Reduction of myocardial infarct size by the calcium antagonist fr 7534. Cardiology. 1981;68(3):146-60. doi: 10.1159/000173276. PMID: 7317884. 2. Jolly SR, Gross GJ. Effect of FR 7534, a new calcium antagonist, on myocardial oxygen demand. Eur J Pharmacol. 1979 Mar 1;54(3):289-93. doi: 10.1016/0014-2999(79)90088-8. PMID: 107031.