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MedKoo Cat#: 575682 | Name: FR-226928 free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FR-226928 free base is a potent antagonist of human neuropeptide Y Y5 receptors.

Chemical Structure

FR-226928 free base
FR-226928 free base
CAS#765261-46-9

Theoretical Analysis

MedKoo Cat#: 575682

Name: FR-226928 free base

CAS#: 765261-46-9

Chemical Formula: C31H41N3O3S

Exact Mass: 535.2869

Molecular Weight: 535.75

Elemental Analysis: C, 69.50; H, 7.71; N, 7.84; O, 8.96; S, 5.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
FR-226928 free base; FR 226928 free base; FR226928 free base
IUPAC/Chemical Name
1-Naphthalenesulfonamide, N-(2-(4-((((6,7,8,9-tetrahydro-3-methoxy-5H-benzocyclohepten-6-yl)methyl)amino)methyl)-1-piperidinyl)ethyl)-
InChi Key
ITJLZSOZZWEOJL-UHFFFAOYSA-N
InChi Code
InChI=1S/C31H41N3O3S/c1-37-29-13-12-26-8-4-6-25(20-28(26)21-29)23-32-22-24-14-17-34(18-15-24)19-16-33-38(35,36)31-11-5-9-27-7-2-3-10-30(27)31/h2-3,5,7,9-13,21,24-25,32-33H,4,6,8,14-20,22-23H2,1H3
SMILES Code
COc1ccc2CCCC(CNCC3CCN(CCNS(=O)(=O)c4cccc5ccccc45)CC3)Cc2c1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 535.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Itani H, Ito H, Sakata Y, Hatakeyama Y, Oohashi H, Satoh Y. Novel potent antagonists of human neuropeptide Y Y5 receptors. Part 2: substituted benzo[a]cycloheptene derivatives. Bioorg Med Chem Lett. 2002 Mar 11;12(5):757-61. doi: 10.1016/s0960-894x(02)00002-1. PMID: 11858996.

View History

FR-227369 free base

FR-227369 free base