CRO15 is a novel inducer of melanoma cell death, activating the AMPK pathway induced by a mitochondrial disorder and inhibiting MELK kinase activity, which inducing cell cycle arrest and activation of DNA damage repair pathways by p53 and REDD1 activation.
MedKoo Cat#: 463804
Name: CRO15
CAS#: unknown
Chemical Formula: C20H14Cl6N10S2
Exact Mass: 667.8975
Molecular Weight: 671.22
Elemental Analysis: C, 35.79; H, 2.10; Cl, 31.69; N, 20.87; S, 9.55
The following data is based on the product molecular weight 671.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
