Fonazine hydrochloride | CAS# 34396-64-0 | Biochemical

MedKoo Cat#: 575613 | Name: Fonazine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fonazine hydrochloride is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist.

Chemical Structure

Fonazine hydrochloride

CAS#34396-64-0

Theoretical Analysis

MedKoo Cat#: 575613

Name: Fonazine hydrochloride

CAS#: 34396-64-0

Chemical Formula: C19H26ClN3O2S2

Exact Mass: 427.1155

Molecular Weight: 428.01

Elemental Analysis: C, 53.32; H, 6.12; Cl, 8.28; N, 9.82; O, 7.48; S, 14.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Fonazine hydrochloride; Fonazine HCl

IUPAC/Chemical Name

10-(2-(Dimethylamino)propyl)-N,N-dimethyl-10H-phenothiazine-2-sulphonamide monohydrochloride

InChi Key

YKXZRFSKLBBPQN-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H25N3O2S2.ClH/c1-14(20(2)3)13-22-16-8-6-7-9-18(16)25-19-11-10-15(12-17(19)22)26(23,24)21(4)5;/h6-12,14H,13H2,1-5H3;1H

SMILES Code

Cl.CC(CN1c2ccccc2Sc3ccc(cc13)S(=O)(=O)N(C)C)N(C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 428.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Takagi H, Takashima M, Liou SY. [Effect of KB-2796, a novel calcium channel blocker, on spreading depression in rat hippocampal slices]. Nihon Yakurigaku Zasshi. 1998 May;111(5):309-16. Japanese. PubMed PMID: 9666486. 2: Shimazawa M, Hara H, Watano T, Sukamoto T. Effects of Ca2+ channel blockers on cortical hypoperfusion and expression of c-Fos-like immunoreactivity after cortical spreading depression in rats. Br J Pharmacol. 1995 Aug;115(8):1359-68. PubMed PMID: 8564192; PubMed Central PMCID: PMC1908864. 3: Castro-Gago M, Couceiro JA, Novo-Rodríguez I, Méndez MJ, Fernández Seara MJ, Eirís J. [Migraine in childhood and adolescence: a retrospective review of hospital cases]. Rev Neurol. 1995 Jul-Aug;23(122):769-72. Spanish. PubMed PMID: 7497237.