Fonazine mesylate | CAS# 13115-40-7 | Biochemical

MedKoo Cat#: 575612 | Name: Fonazine mesylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fonazine mesylate is a phenothiazine drug used for the treatment of migraine. It is a serotonin antagonist and histamine antagonist.

Chemical Structure

Fonazine mesylate

CAS#13115-40-7

Theoretical Analysis

MedKoo Cat#: 575612

Name: Fonazine mesylate

CAS#: 13115-40-7

Chemical Formula: C20H29N3O5S3

Exact Mass: 487.1269

Molecular Weight: 487.65

Elemental Analysis: C, 49.26; H, 5.99; N, 8.62; O, 16.40; S, 19.72

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

8599 R.P. mesylate; Banistyl; Dimethothiazine mesylate; Dimethothiazine methanesulfonate; Fonazine mesylate

IUPAC/Chemical Name

Phenothiazine-2-sulfonamide, 10-(2-(dimethylamino)propyl)-N,N-dimethyl-, monomethanesulfonate

InChi Key

JGKVKXPDDVRUKC-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H25N3O2S2.CH4O3S/c1-14(20(2)3)13-22-16-8-6-7-9-18(16)25-19-11-10-15(12-17(19)22)26(23,24)21(4)5;1-5(2,3)4/h6-12,14H,13H2,1-5H3;1H3,(H,2,3,4)

SMILES Code

CC(CN1c2ccccc2Sc3ccc(cc13)S(=O)(=O)N(C)C)N(C)C.CS(=O)(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 487.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Takagi H, Takashima M, Liou SY. [Effect of KB-2796, a novel calcium channel blocker, on spreading depression in rat hippocampal slices]. Nihon Yakurigaku Zasshi. 1998 May;111(5):309-16. Japanese. PubMed PMID: 9666486. 2: Shimazawa M, Hara H, Watano T, Sukamoto T. Effects of Ca2+ channel blockers on cortical hypoperfusion and expression of c-Fos-like immunoreactivity after cortical spreading depression in rats. Br J Pharmacol. 1995 Aug;115(8):1359-68. PubMed PMID: 8564192; PubMed Central PMCID: PMC1908864. 3: Castro-Gago M, Couceiro JA, Novo-Rodríguez I, Méndez MJ, Fernández Seara MJ, Eirís J. [Migraine in childhood and adolescence: a retrospective review of hospital cases]. Rev Neurol. 1995 Jul-Aug;23(122):769-72. Spanish. PubMed PMID: 7497237.