MedKoo Cat#: 412906 | Name: Cinazepam

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cinazepam is an atypical benzodiazepine derivative. It produces pronounced hypnotic, sedative, and anxiolytic effects with minimal myorelaxant side effects.

Chemical Structure

Cinazepam
Cinazepam
CAS#172986-25-3

Theoretical Analysis

MedKoo Cat#: 412906

Name: Cinazepam

CAS#: 172986-25-3

Chemical Formula: C19H14BrClN2O5

Exact Mass: 463.9775

Molecular Weight: 465.68

Elemental Analysis: C, 49.01; H, 3.03; Br, 17.16; Cl, 7.61; N, 6.02; O, 17.18

Price and Availability

Size Price Availability Quantity
1mg USD 245.00 2 Weeks
5mg USD 583.00 2 Weeks
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Related CAS #
No Data
Synonym
Cinazepam; BD798; BD 798; BD-798
IUPAC/Chemical Name
Butanedioic acid, 1-(7-bromo-5-(2-chlorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepin-3-yl) ester
InChi Key
NQTRBZXDWMDXAQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H14BrClN2O5/c20-10-5-6-14-12(9-10)17(11-3-1-2-4-13(11)21)23-19(18(27)22-14)28-16(26)8-7-15(24)25/h1-6,9,19H,7-8H2,(H,22,27)(H,24,25)
SMILES Code
O=C(OC1C(NC2=CC=C(Br)C=C2C(C3=CC=CC=C3Cl)=N1)=O)CCC(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 465.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Schukin SI, Zinkovsky VG, Zhuk OV. Elimination kinetics of the novel prodrug cinazepam possessing psychotropic activity in mice. Pharmacol Rep. 2011;63(5):1093-100. doi: 10.1016/s1734-1140(11)70628-4. PMID: 22180351. 2: Hok L, BoŽičević L, Sremec H, Šakić D, Vrček V. Racemization of oxazepam and chiral 1,4-benzodiazepines. DFT study of the reaction mechanism in aqueous solution. Org Biomol Chem. 2019 Feb 6;17(6):1471-1479. doi: 10.1039/c8ob02991a. PMID: 30676597. 3: Blednov IuA, Kosach IV, Seredenin SB. Vliianie proizvodnykh 1,4-benzodiazepina na sviazyvanie 35S-tert-butilbitsiklofosoforotionata v mozge inbrednykh mysheĭ s razlichnoĭ émotsional'no-stressovoĭ reaktsieĭ [The effect of 1,4-benzodiazepine derivatives on 35S-tert-butylbicyclophosphorothionate binding in the brain of inbred mice with differing emotional stress reactions]. Eksp Klin Farmakol. 1997 Jul-Aug;60(4):3-6. Russian. PMID: 9376753. 4: Novikov VE. Vliianie proizvodnykh benzodiazepina na formirovanie oteka- nabukhaniia golovnogo mozga v dinamike posttravmaticheskogo perioda [The effect of benzodiazepine derivatives on the formation of brain edema-swelling in the dynamics of the posttraumatic period]. Eksp Klin Farmakol. 1996 May- Jun;59(3):61-3. Russian. PMID: 8974588.