MedKoo Cat#: 575581 | Name: Pavatrine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pavatrine hydrochloride is a biochemical previously studied for its potential use in the treatment of Sphincter of Oddi dysfunction --- a condition that results from the inability of the sphincter to contract and relax in a normal fashion. This may cause obstruction of bile flow resulting in biliary pain and obstruction to the flow of pancreatic juice, which can lead to pancreatitis.

Chemical Structure

Pavatrine hydrochloride
Pavatrine hydrochloride
CAS#548-65-2

Theoretical Analysis

MedKoo Cat#: 575581

Name: Pavatrine hydrochloride

CAS#: 548-65-2

Chemical Formula: C20H24ClNO2

Exact Mass: 345.1496

Molecular Weight: 345.87

Elemental Analysis: C, 69.45; H, 6.99; Cl, 10.25; N, 4.05; O, 9.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Pavatrine hydrochloride; Pavatrine HCl; Ro 2-3208; Robitrin
IUPAC/Chemical Name
Fluorene-9-carboxylic acid, 2-(diethylamino)ethyl ester, hydrochloride
InChi Key
TYFLIJAGRULBIS-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H23NO2.ClH/c1-3-21(4-2)13-14-23-20(22)19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19;/h5-12,19H,3-4,13-14H2,1-2H3;1H
SMILES Code
Cl.CCN(CC)CCOC(=O)C1c2ccccc2c3ccccc13
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 345.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. HOHF RP, IVY AC. The effect of pavatrine (beta-diethylaminoethyl fluorene-9-carboxylate hydrochloride) on the sphincter of Oddi with studies on its toxicity. Q Bull Northwest Univ Med Sch. 1946;20(3):311-4. PMID: 20995365; PMCID: PMC3802671.