MedKoo Cat#: 412888 | Name: Cidoxepin hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cidoxepin hydrochloride is the salt form of Cidoxepin (free base) also known as cis-doxepin or-doxepin, a tricyclic antidepressant which was developed in the 1960s but was never marketed. It is the cis or stereoisomer of doxepin, a mixture of and isomers that is used commercially in a ratio of approximately 85:15 with cidoxepin as a relatively minor constituent.

Chemical Structure

Cidoxepin hydrochloride
Cidoxepin hydrochloride
CAS# 25127-31-5 (HCl)

Theoretical Analysis

MedKoo Cat#: 412888

Name: Cidoxepin hydrochloride

CAS#: 25127-31-5 (HCl)

Chemical Formula: C19H22ClNO

Exact Mass:

Molecular Weight: 315.84

Elemental Analysis: C, 72.25; H, 7.02; Cl, 11.22; N, 4.43; O, 5.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Cidoxepin hydrochloride; Cidoxepin HCl; P4599; P-4599 P 4599
IUPAC/Chemical Name
1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride, (Z)-
InChi Key
MHNSPTUQQIYJOT-CULRIWENSA-N
InChi Code
InChI=1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11-;
SMILES Code
CN(C)CC/C=C1C2=CC=CC=C2OCC3=CC=CC=C\13.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 315.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Milani N, Qiu N, Molitor B, Badée J, Cruciani G, Fowler S. Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10. Drug Metab Dispos. 2020 Mar;48(3):176-186. doi: 10.1124/dmd.119.089482. Epub 2019 Dec 15. PMID: 31839590.