MedKoo Cat#: 575568 | Name: Flurpiridaz

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Flurpiridaz is a biochemical that --- when conjugated with F18 --- may be used to evaluate Coronary Artery Disease.

Chemical Structure

Flurpiridaz
Flurpiridaz
CAS#863888-33-9

Theoretical Analysis

MedKoo Cat#: 575568

Name: Flurpiridaz

CAS#: 863888-33-9

Chemical Formula: C18H22ClFN2O3

Exact Mass: 368.1303

Molecular Weight: 368.83

Elemental Analysis: C, 58.62; H, 6.01; Cl, 9.61; F, 5.15; N, 7.60; O, 13.01

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Flurpiridaz
IUPAC/Chemical Name
3(2H)-Pyridazinone, 4-chloro-2-(1,1-dimethylethyl)-5-((4-((2-fluoroethoxy)methyl)phenyl)methoxy)-
InChi Key
RMXZKEPDYBTFOS-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H22ClFN2O3/c1-18(2,3)22-17(23)16(19)15(10-21-22)25-12-14-6-4-13(5-7-14)11-24-9-8-20/h4-7,10H,8-9,11-12H2,1-3H3
SMILES Code
CC(C)(C)N1N=CC(=C(Cl)C1=O)OCc2ccc(COCCF)cc2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 368.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Maddahi J, Lazewatsky J, Udelson JE, Berman DS, Beanlands RSB, Heller GV, Bateman TM, Knuuti J, Orlandi C. Phase-III Clinical Trial of Fluorine-18 Flurpiridaz Positron Emission Tomography for Evaluation of Coronary Artery Disease. J Am Coll Cardiol. 2020 Jul 28;76(4):391-401. doi: 10.1016/j.jacc.2020.05.063. PMID: 32703509. 2. Gewirtz H, Narula J. A Closer Look at 18Flurpiridaz Data in IHD: Hiding in Plain Sight. J Am Coll Cardiol. 2020 Jul 28;76(4):402-404. doi: 10.1016/j.jacc.2020.06.021. PMID: 32703510. 3. Aljizeeri A, Badarin FA, Al-Mallah MH. Automation in Nuclear Cardiology: Time for Flurpiridaz to Join the Club. J Nucl Cardiol. 2020 Nov 17. doi: 10.1007/s12350-020-02421-9. Epub ahead of print. PMID: 33205327.