MedKoo Cat#: 412842 | Name: Choline dihydrogen citrate
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Choline dihydrogen citrate is a supplement form of choline. It is a white granular to fine crystalline powder and is used to treat liver disease, depression, memory loss, Alzheimer’s disease, dementia, and other mental conditions.

Chemical Structure

Choline dihydrogen citrate
Choline dihydrogen citrate
CAS#77-91-8

Theoretical Analysis

MedKoo Cat#: 412842

Name: Choline dihydrogen citrate

CAS#: 77-91-8

Chemical Formula: C11H21NO8

Exact Mass: 295.1267

Molecular Weight: 295.29

Elemental Analysis: C, 44.74; H, 7.17; N, 4.74; O, 43.34

Price and Availability

Size Price Availability Quantity
25g USD 250.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Choline dihydrogen citrate; Cholex; Citracholine; Delichol
IUPAC/Chemical Name
2-hydroxy-N,N,N-trimethylethan-1-aminium 3-carboxy-2-(carboxymethyl)-2-hydroxypropanoate
InChi Key
WRPUOFKIGGWQIJ-UHFFFAOYSA-M
InChi Code
InChI=1S/C6H8O7.C5H14NO/c7-3(8)1-6(13,5(11)12)2-4(9)10;1-6(2,3)4-5-7/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);7H,4-5H2,1-3H3/q;+1/p-1
SMILES Code
C[N+](C)(CCO)C.OC(CC(CC(O)=O)(C([O-])=O)O)=O
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 295.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Balasundaram S. Choline Dihydrogen Citrate in Infantile Biliary Cirrhosis. Ind Med Gaz. 1947 Dec;82(12):724-726. PMID: 29014818; PMCID: PMC5190556. 2: NEW and nonofficial remedies: choline dihydrogen citrate. J Am Med Assoc. 1950 Jul 1;143(9):815. PMID: 15421841. 3: Lovett TD, Coffey MT, Miles RD, Combs GE. Methionine, choline and sulfate interrelationships in the diet of weanling swine. J Anim Sci. 1986 Aug;63(2):467-71. doi: 10.2527/jas1986.632467x. PMID: 3759683. 4: Weng L, Vijayaraghavan R, Macfarlane DR, Elliott GD. Application of the Kwei equation to model the Tg behavior of binary blends of sugars and salts. Cryobiology. 2014 Feb;68(1):155-8. doi: 10.1016/j.cryobiol.2013.12.005. Epub 2013 Dec 21. PMID: 24365463; PMCID: PMC4101886. 5: Smith PJ, Goeltz JC. Proton-Coupled Electron Transfer and Substituent Effects in Catechol-Based Deep Eutectic Solvents: Gross and Fine Tuning of Redox Activity. J Phys Chem B. 2017 Dec 7;121(48):10974-10978. doi: 10.1021/acs.jpcb.7b10169. Epub 2017 Nov 20. PMID: 29131613. 6: Kaminski DL, Mueller EJ, Jellinek M. Effect of small intestinal bypass on hepatic lipid accumulation in rats. Am J Physiol. 1980 Nov;239(5):G358-62. doi: 10.1152/ajpgi.1980.239.5.G358. PMID: 6108077.