VU0415248 | CAS#unknown | M1R-selective antagonist

MedKoo Cat#: 463701 | Name: VU0415248

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VU0415248 is a M1R-selective antagonist.

Chemical Structure

VU0415248

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 463701

Name: VU0415248

CAS#: unknown

Chemical Formula: C21H23N5O3S

Exact Mass: 425.1522

Molecular Weight: 425.51

Elemental Analysis: C, 59.28; H, 5.45; N, 16.46; O, 11.28; S, 7.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

VU0415248; VU 0415248; VU-0415248;

IUPAC/Chemical Name

N-(3-oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)quinoline-5-sulfonamide

InChi Key

KZEVRYRKBGRMEZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H23N5O3S/c27-21(26-15-13-25(14-16-26)17-6-10-22-11-7-17)8-12-24-30(28,29)20-5-1-4-19-18(20)3-2-9-23-19/h1-7,9-11,24H,8,12-16H2

SMILES Code

O=S(C1=C(C=CC=N2)C2=CC=C1)(NCCC(N3CCN(C4=CC=NC=C4)CC3)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 425.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Melancon BJ, Lamers AP, Bridges TM, Sulikowski GA, Utley TJ, Sheffler DJ, Noetzel MJ, Morrison RD, Daniels JS, Niswender CM, Jones CK, Conn PJ, Lindsley CW, Wood MR. Development of a more highly selective M(1) antagonist from the continued optimization of the MLPCN Probe ML012. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1044-8. doi: 10.1016/j.bmcl.2011.11.110. Epub 2011 Dec 6. PMID: 22197142; PMCID: PMC3434972.