MedKoo Cat#: 575505 | Name: Flazin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Flazin is an Nrf2 pathway activator and potent xanthine oxidase inhibitor.

Chemical Structure

Flazin
Flazin
CAS#100041-05-2

Theoretical Analysis

MedKoo Cat#: 575505

Name: Flazin

CAS#: 100041-05-2

Chemical Formula: C17H12N2O4

Exact Mass: 308.0797

Molecular Weight: 308.29

Elemental Analysis: C, 66.23; H, 3.92; N, 9.09; O, 20.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Flazin; Flazine
IUPAC/Chemical Name
9H-Pyrido(3,4-b)indole-3-carboxylic acid, 1-(5-(hydroxymethyl)-2-furanyl)-
InChi Key
USBWYUYKHHILLZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H12N2O4/c20-8-9-5-6-14(23-9)16-15-11(7-13(19-16)17(21)22)10-3-1-2-4-12(10)18-15/h1-7,18,20H,8H2,(H,21,22)
SMILES Code
OCc1oc(cc1)c2nc(cc3c4ccccc4[nH]c23)C(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 308.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Fuda H, Miyanaga S, Furukawa T, Umetsu S, Joko S, Roan Y, Suzuki H, Hui SP, Watanabe M, Chiba H. Flazin as a Promising Nrf2 Pathway Activator. J Agric Food Chem. 2019 Nov 20;67(46):12844-12853. doi: 10.1021/acs.jafc.9b04600. Epub 2019 Nov 12. PMID: 31668063. 2. Li H, Zhao M, Su G, Lin L, Wang Y. Effect of Soy Sauce on Serum Uric Acid Levels in Hyperuricemic Rats and Identification of Flazin as a Potent Xanthine Oxidase Inhibitor. J Agric Food Chem. 2016 Jun 15;64(23):4725-34. doi: 10.1021/acs.jafc.6b01094. Epub 2016 Jun 2. PMID: 27181598. 3. Tang JG, Wang YH, Wang RR, Dong ZJ, Yang LM, Zheng YT, Liu JK. Synthesis of analogues of flazin, in particular, flazinamide, as promising anti-HIV agents. Chem Biodivers. 2008 Mar;5(3):447-60. doi: 10.1002/cbdv.200890044. PMID: 18357553.