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MedKoo Cat#: 575493 | Name: FLA-63

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FLA-63 is a dopamine-beta-hydroxylase (DBH)-inhibitor and an inhibitor of the last step of noradrenaline biosynthesis.

Chemical Structure

FLA-63
FLA-63
CAS#26087-98-9

Theoretical Analysis

MedKoo Cat#: 575493

Name: FLA-63

CAS#: 26087-98-9

Chemical Formula: C14H26N4S4

Exact Mass: 378.1040

Molecular Weight: 378.63

Elemental Analysis: C, 44.41; H, 6.92; N, 14.80; S, 33.87

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
FLA-63; FLA 63; FLA63
IUPAC/Chemical Name
Disulfide, bis((hexahydro-4-methyl-1H-1,4-diazepin-1-yl)thiocarbonyl)
InChi Key
NXJOFTRBTBDSHB-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H26N4S4/c1-15-5-3-7-17(11-9-15)13(19)21-22-14(20)18-8-4-6-16(2)10-12-18/h3-12H2,1-2H3
SMILES Code
CN1CCCN(CC1)C(=S)SSC(=S)N2CCCN(C)CC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 378.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Tottmar O, Hellström E, Holmberg K, Lindros KO. Effects of dopamine-beta-hydroxylase inhibitors FLA-57 and FLA-63 on ethanol metabolism and aldehyde dehydrogenase activity in rats. Acta Pharmacol Toxicol (Copenh). 1982 Sep;51(3):198-202. doi: 10.1111/j.1600-0773.1982.tb01014.x. PMID: 7136724. 2. Andén NE, Fuxe K. A new dopamine- -hydroxylase inhibitor: effects on the noradrenaline concentration and on the action of L-DOPA in the spinal cord. Br J Pharmacol. 1971 Dec;43(4):747-56. doi: 10.1111/j.1476-5381.1971.tb07210.x. PMID: 4339882; PMCID: PMC1665707.