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MedKoo Cat#: 575490 | Name: FLB-463

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FLB-463 is a high-affinity radioligands for imaging extrastriatal dopamine D(2) receptors in the human brain.

Chemical Structure

FLB-463
FLB-463
CAS#152127-74-7

Theoretical Analysis

MedKoo Cat#: 575490

Name: FLB-463

CAS#: 152127-74-7

Chemical Formula: C16H23BrN2O4

Exact Mass: 386.0841

Molecular Weight: 387.27

Elemental Analysis: C, 49.62; H, 5.99; Br, 20.63; N, 7.23; O, 16.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
(76Br)Flb 463; FLB-463; FLB 463; FLB463
IUPAC/Chemical Name
3-Bromo-N-((1-ethyl-2-pyrrolidinyl)methyl)-5,6-dimethoxysalicylamide
InChi Key
WGLPSCZHULDZSS-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)
SMILES Code
CCN1CCCC1CNC(=O)c2c(O)c(Br)cc(OC)c2OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 387.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. de Paulis T. The discovery of epidepride and its analogs as high-affinity radioligands for imaging extrastriatal dopamine D(2) receptors in human brain. Curr Pharm Des. 2003;9(8):673-96. doi: 10.2174/1381612033391135. PMID: 12570798. 2. Högberg T. The development of dopamine D2-receptor selective antagonists. Drug Des Discov. 1993;9(3-4):333-50. PMID: 8400011.