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MedKoo Cat#: 575489 | Name: Isoremoxipride hydrobromide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Isoremoxipride hydrobromide is a dopamine antagonist.

Chemical Structure

Isoremoxipride hydrobromide
Isoremoxipride hydrobromide
CAS#107188-92-1

Theoretical Analysis

MedKoo Cat#: 575489

Name: Isoremoxipride hydrobromide

CAS#: 107188-92-1

Chemical Formula: C16H24Br2N2O3

Exact Mass: 450.0154

Molecular Weight: 452.19

Elemental Analysis: C, 42.50; H, 5.35; Br, 35.34; N, 6.20; O, 10.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Isoremoxipride hydrobromide; Isoremoxipride HBr; FLB 457 hydrobromide; FLB-457 hydrobromide; FLB457 hydrobromide
IUPAC/Chemical Name
(S)-5-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2,3-dimethoxybenzamide hydrobromide
InChi Key
AOEBIEBXGASRIN-YDALLXLXSA-N
InChi Code
InChI=1S/C16H23BrN2O3.BrH/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3;/h8-9,12H,4-7,10H2,1-3H3,(H,18,20);1H/t12-;/m0./s1
SMILES Code
Br.CCN1CCC[C@H]1CNC(=O)c2cc(Br)cc(OC)c2OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 452.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Narendran R, Jedema HP, Lopresti BJ, Mason NS, Gurnsey K, Ruszkiewicz J, Chen CM, Deuitch L, Frankle WG, Bradberry CW. Imaging dopamine transmission in the frontal cortex: a simultaneous microdialysis and [11C]FLB 457 PET study. Mol Psychiatry. 2014 Mar;19(3):302-10. doi: 10.1038/mp.2013.9. Epub 2013 Feb 26. Erratum in: Mol Psychiatry. 2014 Mar;19(3):399. PMID: 23439486; PMCID: PMC3706503. 2. Narendran R, Mason NS, Chen CM, Himes M, Keating P, May MA, Rabiner EA, Laruelle M, Mathis CA, Frankle WG. Evaluation of dopamine D₂/₃ specific binding in the cerebellum for the positron emission tomography radiotracer [¹¹C]FLB 457: implications for measuring cortical dopamine release. Synapse. 2011 Oct;65(10):991-7. doi: 10.1002/syn.20926. Epub 2011 Apr 26. PMID: 21360596; PMCID: PMC3135684.