MedKoo Cat#: 412792 | Name: Chaetoviridin B

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chaetoviridin B is an organic heterotetracyclic compound that exhibits antifungal activity against plant pathogenic fungi.

Chemical Structure

Chaetoviridin B
Chaetoviridin B
CAS#128230-03-5

Theoretical Analysis

MedKoo Cat#: 412792

Name: Chaetoviridin B

CAS#: 128230-03-5

Chemical Formula: C23H29ClO7

Exact Mass: 452.1602

Molecular Weight: 452.93

Elemental Analysis: C, 60.99; H, 6.45; Cl, 7.83; O, 24.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Chaetoviridin B; ChaetoviridinB; Chaetoviridin-B
IUPAC/Chemical Name
6H-Furo(2,3-h)-2-benzopyran-9-carboxylic acid, 5-chloro-6a,8,9,9a-tetrahydro-8-hydroxy-8-(2-hydroxy-1-methylpropyl)-6a-methyl-3-(3-methyl-1-pentenyl)-6-oxo
InChi Key
TVZGDEYWRLMKPX-BQYQJAHWSA-N
InChi Code
InChI=1S/C23H29ClO7/c1-6-11(2)7-8-14-9-15-16(10-30-14)17-18(21(27)28)23(29,12(3)13(4)25)31-22(17,5)20(26)19(15)24/h7-13,17-18,25,29H,6H2,1-5H3,(H,27,28)/b8-7+
SMILES Code
O=C(C1C(C(C)C(O)C)(O)OC2(C)C1C3=COC(/C=C/C(C)CC)=CC3=C(Cl)C2=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 452.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yue HM, Wang M, Gong WF, Zhang LQ. The screening and identification of the biological control fungi Chaetomium spp. against wheat common root rot. FEMS Microbiol Lett. 2018 Nov 1;365(22). doi: 10.1093/femsle/fny242. PMID: 30289449. 2: Chen GD, Li YJ, Gao H, Chen Y, Li XX, Li J, Guo LD, Cen YZ, Yao XS. New azaphilones and chlorinated phenolic glycosides from Chaetomium elatum with caspase-3 inhibitory activity. Planta Med. 2012 Oct;78(15):1683-9. doi: 10.1055/s-0032-1315211. Epub 2012 Aug 13. PMID: 22890540. 3: Tomoda H, Matsushima C, Tabata N, Namatame I, Tanaka H, Bamberger MJ, Arai H, Fukazawa M, Inoue K, Omura S. Structure-specific inhibition of cholesteryl ester transfer protein by azaphilones. J Antibiot (Tokyo). 1999 Feb;52(2):160-70. doi: 10.7164/antibiotics.52.160. PMID: 10344570. 4: Awad NE, Kassem HA, Hamed MA, El-Naggar MA, El-Feky AM. Bioassays guided isolation of compounds from Chaetomium globosum. J Mycol Med. 2014 Jun;24(2):e35-42. doi: 10.1016/j.mycmed.2013.10.005. Epub 2013 Dec 19. PMID: 24361402. 5: Park JH, Choi GJ, Jang KS, Lim HK, Kim HT, Cho KY, Kim JC. Antifungal activity against plant pathogenic fungi of chaetoviridins isolated from Chaetomium globosum. FEMS Microbiol Lett. 2005 Nov 15;252(2):309-13. doi: 10.1016/j.femsle.2005.09.013. Epub 2005 Sep 21. PMID: 16209910. 6: Youn UJ, Sripisut T, Park EJ, Kondratyuk TP, Fatima N, Simmons CJ, Wall MM, Sun D, Pezzuto JM, Chang LC. Determination of the absolute configuration of chaetoviridins and other bioactive azaphilones from the endophytic fungus Chaetomium globosum. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4719-4723. doi: 10.1016/j.bmcl.2015.08.063. Epub 2015 Aug 24. PMID: 26343828.