Synonym
Chaetoviridin B; ChaetoviridinB; Chaetoviridin-B
IUPAC/Chemical Name
6H-Furo(2,3-h)-2-benzopyran-9-carboxylic acid, 5-chloro-6a,8,9,9a-tetrahydro-8-hydroxy-8-(2-hydroxy-1-methylpropyl)-6a-methyl-3-(3-methyl-1-pentenyl)-6-oxo
InChi Key
TVZGDEYWRLMKPX-BQYQJAHWSA-N
InChi Code
InChI=1S/C23H29ClO7/c1-6-11(2)7-8-14-9-15-16(10-30-14)17-18(21(27)28)23(29,12(3)13(4)25)31-22(17,5)20(26)19(15)24/h7-13,17-18,25,29H,6H2,1-5H3,(H,27,28)/b8-7+
SMILES Code
O=C(C1C(C(C)C(O)C)(O)OC2(C)C1C3=COC(/C=C/C(C)CC)=CC3=C(Cl)C2=O)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
452.93
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Yue HM, Wang M, Gong WF, Zhang LQ. The screening and identification of the biological control fungi Chaetomium spp. against wheat common root rot. FEMS Microbiol Lett. 2018 Nov 1;365(22). doi: 10.1093/femsle/fny242. PMID: 30289449.
2: Chen GD, Li YJ, Gao H, Chen Y, Li XX, Li J, Guo LD, Cen YZ, Yao XS. New azaphilones and chlorinated phenolic glycosides from Chaetomium elatum with caspase-3 inhibitory activity. Planta Med. 2012 Oct;78(15):1683-9. doi: 10.1055/s-0032-1315211. Epub 2012 Aug 13. PMID: 22890540.
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5: Park JH, Choi GJ, Jang KS, Lim HK, Kim HT, Cho KY, Kim JC. Antifungal activity against plant pathogenic fungi of chaetoviridins isolated from Chaetomium globosum. FEMS Microbiol Lett. 2005 Nov 15;252(2):309-13. doi: 10.1016/j.femsle.2005.09.013. Epub 2005 Sep 21. PMID: 16209910.
6: Youn UJ, Sripisut T, Park EJ, Kondratyuk TP, Fatima N, Simmons CJ, Wall MM, Sun D, Pezzuto JM, Chang LC. Determination of the absolute configuration of chaetoviridins and other bioactive azaphilones from the endophytic fungus Chaetomium globosum. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4719-4723. doi: 10.1016/j.bmcl.2015.08.063. Epub 2015 Aug 24. PMID: 26343828.