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MedKoo Cat#: 412773 | Name: Cgs 25015

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cgs 25015 inhibits endothelin-converting enzyme.

Chemical Structure

Cgs 25015
Cgs 25015
CAS#152971-79-4

Theoretical Analysis

MedKoo Cat#: 412773

Name: Cgs 25015

CAS#: 152971-79-4

Chemical Formula: C17H16F3NO3S

Exact Mass: 371.0803

Molecular Weight: 371.37

Elemental Analysis: C, 54.98; H, 4.34; F, 15.35; N, 3.77; O, 12.92; S, 8.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Cgs 25015; Cgs25015; Cgs-25015
IUPAC/Chemical Name
1-Naphthalenepropanoic acid, alpha-((3,3,3-trifluoro-2-(mercaptomethyl)-1-oxopropyl)amino)-
InChi Key
VHNKNFNSIIVFBL-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H16F3NO3S/c18-17(19,20)13(9-25)15(22)21-14(16(23)24)8-11-6-3-5-10-4-1-2-7-12(10)11/h1-7,13-14,25H,8-9H2,(H,21,22)(H,23,24)
SMILES Code
O=C(O)C(NC(C(CS)C(F)(F)F)=O)CC1=C2C=CC=CC2=CC=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 371.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Trapani AJ, Balwierczak JL, Lappe RW, Stanton JL, Graybill SC, Hopkins MF, Savage P, Sperbeck DM, Jeng AY. Effects of metalloprotease inhibitors on the conversion of proendothelin-1 to endothelin-1. Biochem Mol Biol Int. 1993 Dec;31(5):861-7. PMID: 8136704. 2: Savage P, De Lombaert S, Shimada K, Tanzawa K, Jeng AY. Differential inhibition of wild-type endothelin-converting enzyme-1 and its mutants. J Cardiovasc Pharmacol. 1998;31 Suppl 1:S16-8. doi: 10.1097/00005344-199800001-00007. PMID: 9595388. 3: Balwierczak JL, Kukkola PJ, Savage P, Jeng AY. Effects of metalloprotease inhibitors on smooth muscle endothelin-converting enzyme activity. Biochem Pharmacol. 1995 Jan 31;49(3):291-6. doi: 10.1016/0006-2952(94)00508-j. PMID: 7857315.