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MedKoo Cat#: 412752 | Name: CGS-18102A free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CGS-18102A free base is a biochemical

Chemical Structure

CGS-18102A free base
CGS-18102A free base
CAS#100746-35-8

Theoretical Analysis

MedKoo Cat#: 412752

Name: CGS-18102A free base

CAS#: 100746-35-8

Chemical Formula: C16H23NO2

Exact Mass: 261.1729

Molecular Weight: 261.37

Elemental Analysis: C, 73.53; H, 8.87; N, 5.36; O, 12.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CGS-18102A free base; UNII-N120ZZL44H
IUPAC/Chemical Name
(4aR,10bS)-10-methoxy-4-propyl-1,3,4,4a,5,10b-hexahydro-2H-chromeno[3,4-b]pyridine
InChi Key
AIMYJNFPNLKTCY-OLZOCXBDSA-N
InChi Code
InChI=1S/C16H23NO2/c1-3-9-17-10-5-6-12-13(17)11-19-15-8-4-7-14(18-2)16(12)15/h4,7-8,12-13H,3,5-6,9-11H2,1-2H3/t12-,13+/m1/s1
SMILES Code
CCCN1CCC[C@@H]2[C@@H]1COc3c2c(OC)ccc3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 261.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sills MA, Bennett DA, Lovell RA, Liebman JM, Wood PL, Glaeser BS, Williams M, Hutchison AJ. CGS 18102A, a benzopyranopyridine anxiolytic with 5-HT1 agonist and 5-HT2 antagonist properties. Prog Clin Biol Res. 1990;361:469-75. PMID: 1981265. 2: Kleven MS, Assié MB, Koek W. Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT(2A/2C) antagonist anxiolytics. II. Drug discrimination and behavioral observation studies in rats. J Pharmacol Exp Ther. 1997 Aug;282(2):747-59. PMID: 9262338. 3: Kleven MS, Koek W. Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT2A/2C antagonist anxiolytics. I. Antipunishment effects in the pigeon. J Pharmacol Exp Ther. 1996 Feb;276(2):388-97. PMID: 8632301. 4: Leal M, Hayes MJ, Powell ML. Quantitative determination of CGS 18102A, a new anxiolytic, in human plasma using capillary gas chromatography/mass spectrometry. Biomed Chromatogr. 1992 Sep-Oct;6(5):244-7. doi: 10.1002/bmc.1130060509. PMID: 1361157. 5: Stelling MS, Maniara WM, Powell ML. A quantitative analytical method for the determination of a new anxiolytic (CGS 19480A) in human plasma using high performance liquid chromatography. Biomed Chromatogr. 1994 Nov-Dec;8(6):288-90. doi: 10.1002/bmc.1130080607. PMID: 7888731.