FG-5865 | CAS# 150527-35-8 | Biochemical

MedKoo Cat#: 575433 | Name: FG-5865

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FG-5865 potently affects a range of neurochemical indices of rat brain 5-HT neuronal activity in vivo.

Chemical Structure

FG-5865

CAS#150527-35-8

Theoretical Analysis

MedKoo Cat#: 575433

Name: FG-5865

CAS#: 150527-35-8

Chemical Formula: C26H29ClF2N4O

Exact Mass: 486.1998

Molecular Weight: 486.99

Elemental Analysis: C, 64.13; H, 6.00; Cl, 7.28; F, 7.80; N, 11.50; O, 3.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

FG 5865; FG5865; FG-5865

IUPAC/Chemical Name

3-Pyridinecarboxamide, 2-(4-(4,4-bis(4-fluorophenyl)butyl)-1-piperazinyl)-, monohydrochloride

InChi Key

SINUPTNDIYPGBH-UHFFFAOYSA-N

InChi Code

InChI=1S/C27H29F2N3O2.ClH/c1-34-27(33)25-7-3-13-30-26(25)32-17-15-31(16-18-32)14-4-8-24(20-9-11-22(28)12-10-20)21-5-2-6-23(29)19-21;/h2-3,5-7,9-13,19,24H,4,8,14-18H2,1H3;1H

SMILES Code

Cl.COC(=O)c1cccnc1N2CCN(CCCC(c3ccc(F)cc3)c4cccc(F)c4)CC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 486.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Long TA, Kalmus GW, Björk A, Myers RD. Alcohol intake in high alcohol drinking (HAD) rats is suppressed by FG5865, a novel 5-HT1A agonist/5-HT2 antagonist. Pharmacol Biochem Behav. 1996 Jan;53(1):33-40. doi: 10.1016/0091-3057(95)00195-6. PMID: 8848457. 2. Hjorth S, Pettersson G. 5-HT1A autoreceptor-mediated effects of the amperozide congeners, FG5865 and FG5893, on rat brain 5-hydroxytryptamine neurochemistry in vivo. Eur J Pharmacol. 1993 Jul 20;238(2-3):357-67. doi: 10.1016/0014-2999(93)90867-h. PMID: 7691622.