Bendacalol mesylate | CAS# 81737-62-4 | antihypertensive

MedKoo Cat#: 412745 | Name: Bendacalol mesylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bendacalol mesylate is an antihypertensive

Chemical Structure

Bendacalol mesylate

CAS#81737-62-4

Theoretical Analysis

MedKoo Cat#: 412745

Name: Bendacalol mesylate

CAS#: 81737-62-4

Chemical Formula: C21H27NO9S

Exact Mass: 469.1407

Molecular Weight: 469.51

Elemental Analysis: C, 53.72; H, 5.80; N, 2.98; O, 30.67; S, 6.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Bendacalol mesylate; CGS10078B; CGS-10078B; CGS 10078B

IUPAC/Chemical Name

1,4-Benzodioxin-2-methanol, alpha,alpha'-(iminobis(methylene))bis(2,3-dihydro-, (2R*(S*(R*(S*))))-, methanesulfonate (salt)

InChi Key

TWESTNYMJIMXRF-KQWPSRQJSA-N

InChi Code

InChI=1S/C20H23NO6.CH4O3S/c22-13(19-11-24-15-5-1-3-7-17(15)26-19)9-21-10-14(23)20-12-25-16-6-2-4-8-18(16)27-20;1-5(2,3)4/h1-8,13-14,19-23H,9-12H2;1H3,(H,2,3,4)/t13-,14?,19+,20+;/m0./s1

SMILES Code

O[C@@H](CNCC([C@@H]1OC2=CC=CC=C2OC1)O)[C@@H]3OC4=CC=CC=C4OC3.CS(=O)(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 469.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lathers CM, Tumer N, Frame V, Roberts J. Protection of CGS 10078B against ouabain-induced arrhythmia in the cat. Pharmacology. 1987;35(1):35-46. doi: 10.1159/000138293. PMID: 2888137. 2: Gallo A, Kobrin I, Pegram BL, Frohlich ED. The effect of prolonged administration of CGS 10078B on systemic and regional haemodynamics in normotensive and spontaneously hypertensive rats. J Hypertens. 1986 Jun;4(3):351-4. doi: 10.1097/00004872-198606000-00015. PMID: 2874174. 3: Gallo A, Kobrin I, Pegram BL, Frohlich ED. Hemodynamic effects of a new alpha- and beta-adrenergic receptor inhibitor with calcium entry blocking effects (CGS 10078B) in WKY and SHR rats. Am J Med Sci. 1985 Aug;290(2):47-51. doi: 10.1097/00000441-198508000-00001. PMID: 2863983.