MedKoo Cat#: 412724 | Name: VPC 32183 (S)
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

VPC 32183 (S) is a competitive antagonist at the LPA1 and LPA3 receptors. VPC 32183 is devoid of agonist activity at the human LPA1, LPA2 and LPA3 receptors, and, presumably, at other mammalian LPA receptors.

Chemical Structure

VPC 32183 (S)
VPC 32183 (S)
CAS#799268-75-0

Theoretical Analysis

MedKoo Cat#: 412724

Name: VPC 32183 (S)

CAS#: 799268-75-0

Chemical Formula: C33H54N3O6P

Exact Mass: 619.3750

Molecular Weight: 619.78

Elemental Analysis: C, 63.95; H, 8.78; N, 6.78; O, 15.49; P, 5.00

Price and Availability

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1mg USD 328.00 2 Weeks
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Synonym
VPC 32183 (S); (S)-phosphoric acid mono-{2-octadec-9-enoylamino-3-[4-(pyridin-2-ylmethoxy)-phenyl]-propyl} ester (ammonium salt)
IUPAC/Chemical Name
ammonium (S)-2-oleamido-3-(4-(pyridin-2-ylmethoxy)phenyl)propyl hydrogen phosphate
InChi Key
CIWOPVRNKVCACF-OSWNZFOZSA-N
InChi Code
InChI=1S/C33H51N2O6P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-33(36)35-31(28-41-42(37,38)39)26-29-21-23-32(24-22-29)40-27-30-19-17-18-25-34-30;/h9-10,17-19,21-25,31H,2-8,11-16,20,26-28H2,1H3,(H,35,36)(H2,37,38,39);1H3/b10-9-;/t31-;/m0./s1
SMILES Code
O=C(CCCCCCC/C=C\CCCCCCCC)N[C@H](COP(O)([O-])=O)CC1=CC=C(OCC2=CC=CC=N2)C=C1.[NH4+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 619.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Jia W, Tran SK, Ruddick CA, Murph MM. The Src homology 3 binding domain is required for lysophosphatidic acid 3 receptor-mediated cellular viability in melanoma cells. Cancer Lett. 2015 Jan 28;356(2 Pt B):589-96. doi: 10.1016/j.canlet.2014.10.001. Epub 2014 Oct 7. PMID: 25304369.