MedKoo Cat#: 412717 | Name: VU0155056

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VU0155056 is a cell-permeable phospholipase D1 and D2 inhibitor.

Chemical Structure

VU0155056
VU0155056
CAS#1130067-18-3

Theoretical Analysis

MedKoo Cat#: 412717

Name: VU0155056

CAS#: 1130067-18-3

Chemical Formula: C25H26N4O2

Exact Mass: 414.2056

Molecular Weight: 414.51

Elemental Analysis: C, 72.44; H, 6.32; N, 13.52; O, 7.72

Price and Availability

Related CAS #
No Data
Synonym
VU0155056; N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthamide
IUPAC/Chemical Name
N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide
InChi Key
IXLLRNNFUYEADZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H26N4O2/c30-24(20-10-9-18-5-1-2-6-19(18)17-20)26-13-16-28-14-11-21(12-15-28)29-23-8-4-3-7-22(23)27-25(29)31/h1-10,17,21H,11-16H2,(H,26,30)(H,27,31)
SMILES Code
O=C1N(C2CCN(CCNC(C3=CC(C=CC=C4)=C4C=C3)=O)CC2)C5=CC=CC=C5N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 414.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Kumar M, Ojha S1, Rai P, Joshi A, Kamat SS, Mallik R. Insulin activates intracellular transport of lipid droplets to release triglycerides from the liver. J Cell Biol. 2019 Nov 4;218(11):3697-3713. doi: 10.1083/jcb.201903102. Epub 2019 Oct 11. PubMed ID: 31604801 2. Scott SA, Selvy PE, Buck JR, Cho HP, Criswell TL, Thomas AL, Armstrong MD, Arteaga CL, Lindsley CW, Brown HA. Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Biol. 2009 Feb;5(2):108-17. doi: 10.1038/nchembio.140. Epub 2009 Jan 11. PubMed ID: 19136975