Famotine | CAS# 18429-78-2 | Biochemical

MedKoo Cat#: 575301 | Name: Famotine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Famotine is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.

Chemical Structure

Famotine

CAS#18429-78-2

Theoretical Analysis

MedKoo Cat#: 575301

Name: Famotine

CAS#: 18429-78-2

Chemical Formula: C16H14ClNO

Exact Mass: 271.0764

Molecular Weight: 271.74

Elemental Analysis: C, 70.72; H, 5.19; Cl, 13.05; N, 5.15; O, 5.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Famotine

IUPAC/Chemical Name

Isoquinoline, 1-((4-chlorophenoxy)methyl)-3,4-dihydro-

InChi Key

YHDHSSBAHPSMPM-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H14ClNO/c17-13-5-7-14(8-6-13)19-11-16-15-4-2-1-3-12(15)9-10-18-16/h1-8H,9-11H2

SMILES Code

Clc1ccc(OCC2=NCCc3ccccc23)cc1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 271.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Smolinska S, Groeger D, Perez NR, Schiavi E, Ferstl R, Frei R, Konieczna P, Akdis CA, Jutel M, OʼMahony L. Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2016 Jul;22(7):1575-86. doi: 10.1097/MIB.0000000000000825. PubMed PMID: 27271490. 2: Pahs L, Droege C, Kneale H, Pancioli A. A Novel Approach to the Treatment of Orolingual Angioedema After Tissue Plasminogen Activator Administration. Ann Emerg Med. 2016 May 10. pii: S0196-0644(16)00123-2. doi: 10.1016/j.annemergmed.2016.02.019. [Epub ahead of print] PubMed PMID: 27174372. 3: Litou C, Vertzoni M, Goumas C, Vasdekis V, Xu W, Kesisoglou F, Reppas C. Characteristics of the Human Upper Gastrointestinal Contents in the Fasted State Under Hypo- and A-chlorhydric Gastric Conditions Under Conditions of Typical Drug - Drug Interaction Studies. Pharm Res. 2016 Jun;33(6):1399-412. doi: 10.1007/s11095-016-1882-8. Epub 2016 Mar 14. PubMed PMID: 26975361.