Veracevine | CAS# 5876-23-3 | insecticide

MedKoo Cat#: 412624 | Name: Veracevine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Veracevine is an alkaloid that occurs in the seeds of Schoenocaulon officinale. It is used as an insecticide in veterinary medicine.

Chemical Structure

Veracevine

CAS#5876-23-3

Theoretical Analysis

MedKoo Cat#: 412624

Name: Veracevine

CAS#: 5876-23-3

Chemical Formula: C27H43NO8

Exact Mass: 509.2989

Molecular Weight: 509.64

Elemental Analysis: C, 63.63; H, 8.50; N, 2.75; O, 25.11

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Veracevine; Protocevin; NSC127570; NSC-127570; NSC 127570

IUPAC/Chemical Name

Cevane-3-beta,4-beta,12,14,16-beta,17,20-heptol, 4,9-epoxy-

InChi Key

MZHXYVMEVBEFAL-KLGUPHFMSA-N

InChi Code

InChI=1S/C27H43NO8/c1-14-4-7-18-22(3,31)26(34)17(12-28(18)11-14)24(33)13-25-16(23(24,32)10-20(26)30)6-5-15-21(25,2)9-8-19(29)27(15,35)36-25/h14-20,29-35H,4-13H2,1-3H3/t14-,15-,16-,17-,18-,19-,20-,21-,22+,23+,24+,25?,26-,27-/m0/s1

SMILES Code

[H][C@@]12[C@@](O3)(O)[C@@H](O)CC[C@]1(C)C43C[C@@]5(O)[C@]6([H])CN7C[C@@H](C)CC[C@]([H])7[C@@](C)(O)[C@@]6(O)[C@@H](O)C[C@@]5(O)[C@]4([H])CC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 509.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Leibowitz MD, Schwarz JR, Holan G, Hille B. Electrophysiological comparison of insecticide and alkaloid agonists of Na channels. J Gen Physiol. 1987 Jul;90(1):75-93. doi: 10.1085/jgp.90.1.75. PMID: 2442297; PMCID: PMC2228865. 2: Ujváry I, Casida JE. Partial synthesis of 3-O-vanilloylveracevine, an insecticidal alkaloid from Schoenocaulon officinale. Phytochemistry. 1997 Apr;44(7):1257-60. doi: 10.1016/s0031-9422(96)00700-5. PMID: 9115697. 3: Yoshinaka-Niitsu A, Yamagaki T, Harada M, Tachibana K. Solution NMR analysis of the binding mechanism of DIVS6 model peptides of voltage-gated sodium channels and the lipid soluble alkaloid veratridine. Bioorg Med Chem. 2012 May 1;20(9):2796-802. doi: 10.1016/j.bmc.2012.03.034. Epub 2012 Mar 23. PMID: 22483840. 4: SHANES AM, GERSHFELD NL. Interactions of veratrum alkaloids, procaine, and calcium with monolayers of stearic acid and their implications for pharmacological action. J Gen Physiol. 1960 Nov;44(2):345-63. doi: 10.1085/jgp.44.2.345. PMID: 13750673; PMCID: PMC2195101.