MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 412620 | Name: Germerine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Germerine is a biochemical

Chemical Structure

Germerine
Germerine
CAS#508-67-8

Theoretical Analysis

MedKoo Cat#: 412620

Name: Germerine

CAS#: 508-67-8

Chemical Formula: C37H59NO11

Exact Mass: 693.4088

Molecular Weight: 693.88

Elemental Analysis: C, 64.05; H, 8.57; N, 2.02; O, 25.36

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Germerine; UNII-9V3T5CCW5U
IUPAC/Chemical Name
Cevane-3,4,7,14,15,16,20-heptol, 4,9-epoxy-, 3-(2-hydroxy-2-methylbutanoate) 15-(2-methylbutanoate), (3beta(S),4alpha,7alpha,15alpha(R),16beta)-
InChi Key
JOBMMOBXVRRLOS-GIQIJVODSA-N
InChi Code
InChI=1S/C37H59NO11/c1-8-19(4)30(41)48-29-27(40)26-20(17-38-16-18(3)10-11-24(38)34(26,7)44)21-15-35-28(36(21,29)45)22(39)14-23-32(35,5)13-12-25(37(23,46)49-35)47-31(42)33(6,43)9-2/h18-29,39-40,43-46H,8-17H2,1-7H3/t18-,19?,20-,21-,22+,23-,24-,25-,26+,27+,28+,29-,32-,33?,34+,35+,36-,37-/m0/s1
SMILES Code
[H][C@@]12[C@@](O3)(O)[C@@H](OC(C(C)(O)CC)=O)CC[C@]1(C)[C@@]43C[C@@]5([H])[C@]6([H])CN7C[C@@H](C)CC[C@]([H])7[C@@](C)(O)[C@]([H])6[C@@H](O)[C@H](OC(C(C)CC)=O)[C@@]5(O)[C@]4([H])[C@H](O)C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 693.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: WANG SC, NGAI SH, GROSSMAN RG. Mechanism of vasomotor action of Veratrum alkaloids: extravagal sites of action of veriloid, protoveratrine, germitrine, neogermitrine, germerine, veratridine and veratramine. J Pharmacol Exp Ther. 1955 Jan;113(1):100-14. PMID: 13234032. 2: Kimura I, Islam A, Honda R, Nojima H, Tezuka Y, Zhao W. Blood-pressure lowering, positive chronotropy and inotropy by the Veratrum alkaloids germidine and germerine but negative chronotropy by veratridine in mice. J Asian Nat Prod Res. 2000;2(2):133-44. doi: 10.1080/10286020008039902. PMID: 11252678. 3: Cong Y, Guo L, Yang JY, Li L, Zhou YB, Chen J, Wang JH. Steroidal alkaloids from Veratrum japonicum with genotoxicity on brain cell DNA of the cerebellum and cerebral cortex in mice. Planta Med. 2007 Dec;73(15):1588-91. doi: 10.1055/s-2007-993750. Epub 2007 Dec 11. PMID: 18074316.