MedKoo Cat#: 463534 | Name: SB335573

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SB335573 is a potent, selective hERG potassium channel (Kv11.1) activator.

Chemical Structure

SB335573
SB335573
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 463534

Name: SB335573

CAS#: unknown

Chemical Formula: C14H10Cl2N6O

Exact Mass: 348.0293

Molecular Weight: 349.18

Elemental Analysis: C, 48.16; H, 2.89; Cl, 20.31; N, 24.07; O, 4.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SB335573; SB 335573; SB-335573;
IUPAC/Chemical Name
1-(4-chloro-2-(1H-tetrazol-5-yl)phenyl)-3-(4-chlorophenyl)urea
InChi Key
LQDYKPUMNVSNKY-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H10Cl2N6O/c15-8-1-4-10(5-2-8)17-14(23)18-12-6-3-9(16)7-11(12)13-19-21-22-20-13/h1-7H,(H2,17,18,23)(H,19,20,21,22)
SMILES Code
ClC1=CC=C(NC(NC2=CC=C(Cl)C=C2)=O)C(C3=NN=NN3)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 349.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Donovan BT, Bandyopadhyay D, Duraiswami C, Nixon CJ, Townsend CY, Martens SF. Discovery and electrophysiological characterization of SKF-32802: A novel hERG agonist found through a large-scale structural similarity search. Eur J Pharmacol. 2018 Jan 5;818:306-327. doi: 10.1016/j.ejphar.2017.10.015. Epub 2017 Oct 16. PMID: 29050968.