LCX001 | CAS#unknown | AMPA Receptor Modulator

MedKoo Cat#: 463531 | Name: LCX001

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LCX001 is a Novel Allosteric AMPA Receptor Modulator.

Chemical Structure

LCX001

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 463531

Name: LCX001

CAS#: unknown

Chemical Formula: C14H17N3O3

Exact Mass: 275.1270

Molecular Weight: 275.31

Elemental Analysis: C, 61.08; H, 6.22; N, 15.26; O, 17.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LCX001; LCX 001; LCX-001;

IUPAC/Chemical Name

N-((1r,4r)-4-hydroxycyclohexyl)-N-methylbenzo[c][1,2,5]oxadiazole-5-carboxamide

InChi Key

RJSPKJWOSVQMSH-XYPYZODXSA-N

InChi Code

InChI=1S/C14H17N3O3/c1-17(10-3-5-11(18)6-4-10)14(19)9-2-7-12-13(8-9)16-20-15-12/h2,7-8,10-11,18H,3-6H2,1H3/t10-,11-

SMILES Code

O[C@@H]1CC[C@@H](N(C)C(C2=CC3=NON=C3C=C2)=O)CC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 275.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dai W, Gao X, Xiao D, Li YL, Zhou XB, Yong Z, Su RB. The Impact and Mechanism of a Novel Allosteric AMPA Receptor Modulator LCX001 on Protection Against Respiratory Depression in Rodents. Front Pharmacol. 2019 Feb 19;10:105. doi: 10.3389/fphar.2019.00105. PMID: 30837875; PMCID: PMC6389625. 2: Xiao D, Meng FH, Dai W, Yong Z, Liu JQ, Zhou XB, Li S. Design, Synthesis and Biological Evaluation of Brain-Targeted Thiamine Disulfide Prodrugs of Ampakine Compound LCX001. Molecules. 2016 Apr 14;21(4):488. doi: 10.3390/molecules21040488. PMID: 27089316; PMCID: PMC6274124.