BPAM-344 is a Positive Allosteric Modulator of Kainate Receptor. BPAM344 potentiated glutamate-evoked currents of GluK2a 21-fold at the highest concentration tested (200 μM), with an EC50 of 79 μM. BPAM344 markedly decreased desensitization kinetics (from 5.5 to 775 ms).
MedKoo Cat#: 463528
Name: BPAM-344
CAS#: 1204572-55-3
Chemical Formula: C10H11FN2O2S
Exact Mass: 242.0525
Molecular Weight: 242.27
Elemental Analysis: C, 49.58; H, 4.58; F, 7.84; N, 11.56; O, 13.21; S, 13.23
The following data is based on the product molecular weight 242.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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