MedKoo Cat#: 463487 | Name: Suprastat
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Suprastat is a novel Selective Histone Deacetylase 6 (HDAC6) Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.

Chemical Structure

Suprastat
Suprastat
CAS#90093-40-6

Theoretical Analysis

MedKoo Cat#: 463487

Name: Suprastat

CAS#: 90093-40-6

Chemical Formula: C20H26N4O4

Exact Mass: 386.1954

Molecular Weight: 386.45

Elemental Analysis: C, 62.16; H, 6.78; N, 14.50; O, 16.56

Price and Availability

Size Price Availability Quantity
10mg USD 750.00 2 Weeks
25mg USD 1,350.00 2 Weeks
50mg USD 2,350.00 2 Weeks
100mg USD 3,950.00 2 Weeks
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Related CAS #
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Synonym
Suprastat;
IUPAC/Chemical Name
4-((3-(4-(aminomethyl)phenyl)-1-(4-hydroxybutyl)ureido)methyl)-N-hydroxybenzamide
InChi Key
VTRGFHYHEAEHGS-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H26N4O4/c21-13-15-5-9-18(10-6-15)22-20(27)24(11-1-2-12-25)14-16-3-7-17(8-4-16)19(26)23-28/h3-10,25,28H,1-2,11-14,21H2,(H,22,27)(H,23,26)
SMILES Code
O=C(NO)C1=CC=C(CN(CCCCO)C(NC2=CC=C(CN)C=C2)=O)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 386.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Noonepalle S, Shen S, Ptáček J, Tavares MT, Zhang G, Stránský J, Pavlíček J, Ferreira GM, Hadley M, Pelaez G, Bařinka C, Kozikowski AP, Villagra A. Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models. J Med Chem. 2020 Sep 24;63(18):10246-10262. doi: 10.1021/acs.jmedchem.0c00567. Epub 2020 Sep 2. PMID: 32815366.