AV-153 disodium | CAS# 52148-45-5 | Biochemical

MedKoo Cat#: 575119 | Name: AV-153 disodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AV-153 disodium is a biochemical with antimutagenic activity.

Chemical Structure

AV-153 disodium

CAS#52148-45-5

Theoretical Analysis

MedKoo Cat#: 575119

Name: AV-153 disodium

CAS#: 52148-45-5

Chemical Formula: C15H17NNa2O6

Exact Mass: 353.0851

Molecular Weight: 353.28

Elemental Analysis: C, 51.00; H, 4.85; N, 3.96; Na, 13.01; O, 27.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

27296-05-5 (free base)

Synonym

AV-153 disodium; AV153 disodium; AV 153 disodium

IUPAC/Chemical Name

1,4(4H)-Pyridinedicarboxylic acid, 2,6-dimethyl-3,5-bis(1-oxopropyl)-, sodium salt

InChi Key

HDHYGBRYOGZWNP-UHFFFAOYSA-L

InChi Code

InChI=1S/C15H19NO6.2Na/c1-5-9(17)11-7(3)16(15(21)22)8(4)12(10(18)6-2)13(11)14(19)20;;/h13H,5-6H2,1-4H3,(H,19,20)(H,21,22);;/q;2*+1/p-2

SMILES Code

[Na+].[Na+].CCC(=O)C1=C(C)N(C(=O)[O-])C(=C(C1C(=O)[O-])C(=O)CC)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 353.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Leonova E, Rostoka E, Sauvaigo S, Baumane L, Selga T, Sjakste N. Study of interaction of antimutagenic 1,4-dihydropyridine AV-153-Na with DNA-damaging molecules and its impact on DNA repair activity. PeerJ. 2018 Apr 25;6:e4609. doi: 10.7717/peerj.4609. PMID: 29713564; PMCID: PMC5923214. 2. Buraka E, Chen CY, Gavare M, Grube M, Makarenkova G, Nikolajeva V, Bisenieks I, Brūvere I, Bisenieks E, Duburs G, Sjakste N. DNA-binding studies of AV-153, an antimutagenic and DNA repair-stimulating derivative of 1,4-dihydropiridine. Chem Biol Interact. 2014 Sep 5;220:200-7. doi: 10.1016/j.cbi.2014.06.027. Epub 2014 Jul 10. PMID: 25016077.