Amicoumacin B is an amicoumacin that has been found in N. jinanensis and has quorum-sensing inhibitory activity. It is active against C. violaceum and reduces the expression of the C. violaceum operons vioA, vioB, vioD, and vioE, but increases the expression of vioC, indicating quorum sensing inhibitory activity. Amicoumacin B increases the expression of bone morphogenetic protein 2 (BMP2) in MG-63 cells.
MedKoo Cat#: 463456
Name: Amicoumacin B
CAS#: 82768-33-0
Chemical Formula: C20H28N2O8
Exact Mass: 424.1846
Molecular Weight: 424.45
Elemental Analysis: C, 56.60; H, 6.65; N, 6.60; O, 30.15
The following data is based on the product molecular weight 424.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
