BTA-EG6 | CAS#921193-29-5 | Catalase-amyloid interaction inhibitor

MedKoo Cat#: 463443 | Name: BTA-EG6

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BTA-EG6 is a novel catalase-amyloid interaction inhibitor, penetrating the blood-brain barrier and protecting cells from Aβ-induced toxicity.

Chemical Structure

BTA-EG6

CAS#921193-29-5

Theoretical Analysis

MedKoo Cat#: 463443

Name: BTA-EG6

CAS#: 921193-29-5

Chemical Formula: C26H36N2O6S

Exact Mass: 504.2294

Molecular Weight: 504.64

Elemental Analysis: C, 61.88; H, 7.19; N, 5.55; O, 19.02; S, 6.35

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

BTA-EG6; BTAEG6; BTA EG6;

IUPAC/Chemical Name

17-((4-(6-methylbenzo[d]thiazol-2-yl)phenyl)amino)-3,6,9,12,15-pentaoxaheptadecan-1-ol

InChi Key

WMUQNKONZAVRQD-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H36N2O6S/c1-21-2-7-24-25(20-21)35-26(28-24)22-3-5-23(6-4-22)27-8-10-30-12-14-32-16-18-34-19-17-33-15-13-31-11-9-29/h2-7,20,27,29H,8-19H2,1H3

SMILES Code

CC1=CC=C2N=C(C3=CC=C(C=C3)NCCOCCOCCOCCOCCOCCO)SC2=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 504.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Cifelli JL, Chung TS, Liu H, Prangkio P, Mayer M, Yang J. Benzothiazole Amphiphiles Ameliorate Amyloid β-Related Cell Toxicity and Oxidative Stress. ACS Chem Neurosci. 2016 Jun 15;7(6):682-8. doi: 10.1021/acschemneuro.6b00085. Epub 2016 Apr 12. PMID: 27055069. 2: Lee NJ, Song JM, Cho HJ, Sung YM, Lee T, Chung A, Hong SH, Cifelli JL, Rubinshtein M, Habib LK, Capule CC, Turner RS, Pak DT, Yang J, Hoe HS. Hexa (ethylene glycol) derivative of benzothiazole aniline promotes dendritic spine formation through the RasGRF1-Ras dependent pathway. Biochim Biophys Acta. 2016 Feb;1862(2):284-95. doi: 10.1016/j.bbadis.2015.12.007. Epub 2015 Dec 8. PMID: 26675527. 3: Duan JM, Qiu JY, Tan SY, Liu SW, Li L. [Semen-derived enhancer of viral infection--a key factor in sexual transmission of HIV]. Bing Du Xue Bao. 2012 Jan;28(1):84-8. Chinese. PMID: 22416356.