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MedKoo Cat#: 575083 | Name: Gougerotin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Gougerotin is an inhibitor of protein synthesis.

Chemical Structure

Gougerotin
Gougerotin
CAS#2096-42-6

Theoretical Analysis

MedKoo Cat#: 575083

Name: Gougerotin

CAS#: 2096-42-6

Chemical Formula: C16H25N7O8

Exact Mass: 443.1765

Molecular Weight: 443.42

Elemental Analysis: C, 43.34; H, 5.68; N, 22.11; O, 28.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Antibiotic 21544; Aspiculamycin; Asteromycin; Gougerotin; Quingfengmycin
IUPAC/Chemical Name
(2S,3S,4S,5R,6R)-6-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,5-dihydroxy-3-((R)-3-hydroxy-2-(2-(methylamino)acetamido)propanamido)tetrahydro-2H-pyran-2-carboxamide
InChi Key
AMNAZJFEONUVTD-QJHHURCWSA-N
InChi Code
InChI=1S/C16H25N7O8/c1-19-4-8(25)20-6(5-24)14(29)22-9-10(26)11(27)15(31-12(9)13(18)28)23-3-2-7(17)21-16(23)30/h2-3,6,9-12,15,19,24,26-27H,4-5H2,1H3,(H2,18,28)(H,20,25)(H,22,29)(H2,17,21,30)/t6-,9+,10+,11-,12+,15-/m1/s1
SMILES Code
CNCC(=O)N[C@H](CO)C(=O)N[C@H]1[C@H](O)[C@@H](O)[C@@H](O[C@@H]1C(=O)N)N2C=CC(=NC2=O)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 443.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Du D, Zhu Y, Wei J, Tian Y, Niu G, Tan H. Improvement of gougerotin and nikkomycin production by engineering their biosynthetic gene clusters. Appl Microbiol Biotechnol. 2013 Jul;97(14):6383-96. doi: 10.1007/s00253-013-4836-7. Epub 2013 Mar 21. PMID: 23515837. 2. Yukioka M, Morisawa S. Studies on the mechanism of action of gougerotin. II. Effect of various factors on gougerotin action. J Biochem. 1969 Aug;66(2):233-9. doi: 10.1093/oxfordjournals.jbchem.a129139. PMID: 4899689. 3. Ikeuchi T, Kitame F, Kikuchi M, Ishida N. An antimycoplasma antibiotic asteromycin: its identity with gougerotin. J Antibiot (Tokyo). 1972 Sep;25(9):548-50. doi: 10.7164/antibiotics.25.548. PMID: 4645955.