MedKoo Cat#: 575081 | Name: ASP2397

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ASP2397 is an antifungal.

Chemical Structure

ASP2397
ASP2397
CAS#1186200-57-6

Theoretical Analysis

MedKoo Cat#: 575081

Name: ASP2397

CAS#: 1186200-57-6

Chemical Formula: C40H59AlN10O13

Exact Mass: 914.4078

Molecular Weight: 914.95

Elemental Analysis: C, 52.51; H, 6.50; Al, 2.95; N, 15.31; O, 22.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
ASP2397; ASP 2397; ASP-2397; VL-2397; VL2397; VL 2397
IUPAC/Chemical Name
Cyclo(L-asparaginyl-L-leucyl-D-phenylalanyl-N5-acetyl-N5-hydroxy-L-ornithyl-N5-acetyl-N5-hydroxy-L-ornithyl-N5-acetyl-N5-hydroxy-L-ornithyl), aluminum salt (1:1)
InChi Key
NRHTWBFQTMOOKS-FELWXBABSA-N
InChi Code
InChI=1S/C40H59N10O13.Al/c1-23(2)20-31-38(58)46-32(21-27-12-7-6-8-13-27)39(59)44-29(15-10-18-49(62)25(4)52)36(56)42-28(14-9-17-48(61)24(3)51)35(55)43-30(16-11-19-50(63)26(5)53)37(57)47-33(22-34(41)54)40(60)45-31;/h6-8,12-13,23,28-33H,9-11,14-22H2,1-5H3,(H2,41,54)(H,42,56)(H,43,55)(H,44,59)(H,45,60)(H,46,58)(H,47,57);/q-3;+3/t28-,29-,30-,31-,32+,33-;/m0./s1
SMILES Code
[Al+3].CC(C)C[C@@H]1NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCCN([O-])C(=O)C)NC(=O)[C@H](CCCN([O-])C(=O)C)NC(=O)[C@H](CCCN([O-])C(=O)C)NC(=O)[C@@H](Cc2ccccc2)NC1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 914.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Nakamura I, Ohsumi K, Takeda S, Katsumata K, Matsumoto S, Akamatsu S, Mitori H, Nakai T. ASP2397 Is a Novel Natural Compound That Exhibits Rapid and Potent Fungicidal Activity against Aspergillus Species through a Specific Transporter. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e02689-18. doi: 10.1128/AAC.02689-18. PMID: 31405853; PMCID: PMC6761492. 2. Nakamura I, Yoshimura S, Masaki T, Takase S, Ohsumi K, Hashimoto M, Furukawa S, Fujie A. ASP2397: a novel antifungal agent produced by Acremonium persicinum MF-347833. J Antibiot (Tokyo). 2017 Jan;70(1):45-51. doi: 10.1038/ja.2016.107. Epub 2016 Sep 7. PMID: 27599768.