ASI-254 | CAS# 65955-49-9 | Biochemical

MedKoo Cat#: 575052 | Name: ASI-254

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ASI-254 is an aminosugar cardiac glycoside and an inhibitor of Na+,K+ -ATPase.

Chemical Structure

ASI-254

CAS#65955-49-9

Theoretical Analysis

MedKoo Cat#: 575052

Name: ASI-254

CAS#: 65955-49-9

Chemical Formula: C29H45NO7

Exact Mass: 519.3196

Molecular Weight: 519.68

Elemental Analysis: C, 67.03; H, 8.73; N, 2.70; O, 21.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

ASI-254; ASI 254; ASI254

IUPAC/Chemical Name

Card-20(22)enolide, 3-((4-amino-4,6-dideoxy-beta-D-glucopyranosyl)oxy)-14-hydroxy-, (3beta,5beta)-

InChi Key

IDPDVBWYOPBDLZ-DHJPIHCVSA-N

InChi Code

InChI=1S/C29H45NO7/c1-15-23(30)24(32)25(33)26(36-15)37-18-6-9-27(2)17(13-18)4-5-21-20(27)7-10-28(3)19(8-11-29(21,28)34)16-12-22(31)35-14-16/h12,15,17-21,23-26,32-34H,4-11,13-14,30H2,1-3H3/t15-,17-,18+,19-,20+,21-,23-,24+,25-,26+,27+,28-,29?/m1/s1

SMILES Code

C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)[C@H](CC[C@@H]4[C@@H]3CC[C@]5(C)[C@H](CCC45O)C6=CC(=O)OC6)C2)[C@H](O)[C@@H](O)[C@@H]1N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 519.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Puryear SK, Nash CB, Caldwell RW. Effect of cardiac beta-adrenergic blockade or denervation on cardiotoxicity of digoxin and an aminosugar cardenolide. J Cardiovasc Pharmacol. 1981 Jan-Feb;3(1):113-27. PMID: 6160341. 2. Caldwell RW, Nash CB. Comparison of the effects of aminosugar cardiac glycosides with ouabain and digoxin on Na+, K+ -adenosine triphosphatase and cardiac contractile force. J Pharmacol Exp Ther. 1978 Jan;204(1):141-8. PMID: 145490.