MedKoo Cat#: 575045 | Name: AS-1410

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AS-1410 is a biochemical.

Chemical Structure

AS-1410
CAS#1173659-25-0

Theoretical Analysis

MedKoo Cat#: 575045

Name: AS-1410

CAS#: 1173659-25-0

Chemical Formula: C34H38F2N6O2

Exact Mass: 600.3024

Molecular Weight: 600.71

Elemental Analysis: C, 67.98; H, 6.38; F, 6.33; N, 13.99; O, 5.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
AS-1410, AS 1410, AS1410; BSG-17; BSG 17; BSG17
IUPAC/Chemical Name
1-Pyrrolidinepropanamide, N,N'-(9-(((3,4-difluorophenyl)methyl)amino)-3,6-acridinediyl)bis-
InChi Key
NGMQRZIFCCYTRG-UHFFFAOYSA-N
InChi Code
1S/C34H38F2N6O2/c35-28-10-5-23(19-29(28)36)22-37-34-26-8-6-24(38-32(43)11-17-41-13-1-2-14-41)20-30(26)40-31-21-25(7-9-27(31)34)39-33(44)12-18-42-15-3-4-16-42/h5-10,19-21H,1-4,11-18,22H2,(H,37,40)(H,38,43)(H,39,44)
SMILES Code
Fc1ccc(CNc2c3ccc(NC(=O)CCN4CCCC4)cc3nc5cc(NC(=O)CCN6CCCC6)ccc25)cc1F
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 600.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Kelland LR. Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics--current status and future prospects. Eur J Cancer. 2005 May;41(7):971-9. doi: 10.1016/j.ejca.2004.11.024. PMID: 15862745. 2. Gunaratnam M, Green C, Moreira JB, Moorhouse AD, Kelland LR, Moses JE, Neidle S. G-quadruplex compounds and cis-platin act synergistically to inhibit cancer cell growth in vitro and in vivo. Biochem Pharmacol. 2009 Jul 15;78(2):115-22. doi: 10.1016/j.bcp.2009.03.018. PMID: 19475728.