MedKoo Cat#: 575040 | Name: Articulin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Articulin is a member of a new class of membrane cytoskeletal proteins. 80 & 86 kDa proteins in equimolar amounts make up 60% of the peripheral membrane skeleton.

Chemical Structure

Articulin
CAS#75478-98-7

Theoretical Analysis

MedKoo Cat#: 575040

Name: Articulin

CAS#: 75478-98-7

Chemical Formula: C20H26O5

Exact Mass: 346.1780

Molecular Weight: 346.42

Elemental Analysis: C, 69.34; H, 7.57; O, 23.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
Synonym
Articulin; 80 kD Articulin; 86 kD Articulin
IUPAC/Chemical Name
1H-Naphtho(1,8a-c)furan-3(5H)-one, 7-(2-(2,5-dihydro-5-oxo-3-furanyl)ethyl)-6,6a,7,8,9,10-hexahydro-5-hydroxy-7,8-dimethyl-, (5S-(5alpha,6aalpha,7alpha,8beta,10aR*))-
InChi Key
CIYUVACHWWSUHM-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H26O5/c1-12-3-6-20-11-25-18(23)15(20)8-14(21)9-16(20)19(12,2)5-4-13-7-17(22)24-10-13/h7-8,12,14,16,21H,3-6,9-11H2,1-2H3
SMILES Code
CC1CCC23COC(=O)C2=CC(O)CC3C1(C)CCC4=CC(=O)OC4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 346.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Marrs JA, Bouck GB. The two major membrane skeletal proteins (articulins) of Euglena gracilis define a novel class of cytoskeletal proteins. J Cell Biol. 1992 Sep;118(6):1465-75. doi: 10.1083/jcb.118.6.1465. PMID: 1522117; PMCID: PMC2289617. 2. Tremp AZ, Khater EI, Dessens JT. IMC1b is a putative membrane skeleton protein involved in cell shape, mechanical strength, motility, and infectivity of malaria ookinetes. J Biol Chem. 2008 Oct 10;283(41):27604-11. doi: 10.1074/jbc.M801302200. Epub 2008 Jul 23. PMID: 18650444; PMCID: PMC2562075.