Tryparsamide | CAS# 554-72-3 | Biochemical

MedKoo Cat#: 575031 | Name: Tryparsamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tryparsamide is an arsenic compound with activity against Spirochaetes bacteria. Tryparsamide is used in the treatment of syphilis and African sleeping sickness.

Chemical Structure

Tryparsamide

CAS#554-72-3

Theoretical Analysis

MedKoo Cat#: 575031

Name: Tryparsamide

CAS#: 554-72-3

Chemical Formula: C8H10AsN2NaO4

Exact Mass: 295.9754

Molecular Weight: 296.09

Elemental Analysis: C, 32.45; H, 3.40; As, 25.30; N, 9.46; Na, 7.76; O, 21.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Novatoxyl; Tryparsamide; Tryparsone; Tryponarsyl; Trypothane

IUPAC/Chemical Name

Arsanilic acid, N-(carbamoylmethyl)-, monosodium salt

InChi Key

UEYIAABRKWHXJV-UHFFFAOYSA-M

InChi Code

InChI=1S/C8H11AsN2O4.Na/c10-8(12)5-11-7-3-1-6(2-4-7)9(13,14)15;/h1-4,11H,5H2,(H2,10,12)(H2,13,14,15);/q;+1/p-1

SMILES Code

[Na+].NC(=O)CNc1ccc(cc1)[As](=O)(O)[O-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 296.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1.Thomson KD. Tryparsamide. Lancet. 1989 Sep 2;2(8662):573. doi: 10.1016/s0140-6736(89)90704-6. PMID: 2570279. 2. Pearce L. TRYPARSAMIDE TREATMENT OF AFRICAN SLEEPING SICKNESS. Science. 1925 Jan 23;61(1569):90-2. doi: 10.1126/science.61.1569.90-b. PMID: 17807325. 3. Ollivier G, Legros D. Trypanosomiase humaine africaine: histroique de la thérapeutique et de ses échecs [Human african trypanosomiasis: A history of its therapies and their failures]. Trop Med Int Health. 2001 Nov;6(11):855-63. French. doi: 10.1046/j.1365-3156.2001.00753.x. PMID: 11703839.