TAMRA-EdATP | CAS#unknown | Fluorescent dATP

MedKoo Cat#: 463362 | Name: TAMRA-EdATP

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TAMRA-EdATP is a novel Fluorescent dATP for DNA Synthesis In Vivo, exhibited high brightness, low toxicity, and rapid incorporation and depletion kinetics in both a vertebrate (zebrafish) and a nematode (Caenorhabditis elegans).

Chemical Structure

TAMRA-EdATP

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 463362

Name: TAMRA-EdATP

CAS#: unknown

Chemical Formula: C41H41N10Na4O16P3

Exact Mass: 1114.1506

Molecular Weight: 1114.71

Elemental Analysis: C, 44.18; H, 3.71; N, 12.57; Na, 8.25; O, 22.96; P, 8.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

TAMRA-EdATP; TAMRA EdATP;

IUPAC/Chemical Name

sodium 5-((3-(4-(4-amino-7-((2R,4S,5R)-4-hydroxy-5-(((oxido((oxido(phosphonatooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-1H-1,2,3-triazol-1-yl)propyl)carbamoyl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)benzoate

InChi Key

XKVCIHHOLVTRHX-PORHHMETSA-J

InChi Code

InChI=1S/C41H45N10O16P3.4Na/c1-48(2)23-7-10-26-32(15-23)64-33-16-24(49(3)4)8-11-27(33)36(26)25-9-6-22(14-28(25)41(54)55)40(53)43-12-5-13-50-19-30(46-47-50)29-18-51(39-37(29)38(42)44-21-45-39)35-17-31(52)34(65-35)20-63-69(59,60)67-70(61,62)66-68(56,57)58;;;;/h6-11,14-16,18-19,21,31,34-35,52H,5,12-13,17,20H2,1-4H3,(H7-,42,43,44,45,53,54,55,56,57,58,59,60,61,62);;;;/q;4*+1/p-4/t31-,34+,35+;;;;/m0..../s1

SMILES Code

O=C([O-])C1=CC(C(NCCCN2N=NC(C3=CN([C@@H]4O[C@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)[C@@H](O)C4)C5=NC=NC(N)=C53)=C2)=O)=CC=C1C6=C7C=C/C(C=C7OC8=C6C=CC(N(C)C)=C8)=[N+](C)/C.[Na+].[Na+].[Na+].[Na+]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,114.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Schreier VN, Loehr MO, Deng T, Lattmann E, Hajnal A, Neuhauss SCF, Luedtke NW. Fluorescent dATP for DNA Synthesis In Vivo. ACS Chem Biol. 2020 Oct 27. doi: 10.1021/acschembio.0c00654. Epub ahead of print. PMID: 33108866.