MedKoo Cat#: 575012 | Name: Aristololactam

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aristololactam is a metabolite of aristolochic acid that forms DNA adducts -- a segment of DNA bound to a cancer-causing chemical.

Chemical Structure

Aristololactam
Aristololactam
CAS#13395-02-3

Theoretical Analysis

MedKoo Cat#: 575012

Name: Aristololactam

CAS#: 13395-02-3

Chemical Formula: C17H11NO4

Exact Mass: 293.0688

Molecular Weight: 293.28

Elemental Analysis: C, 69.62; H, 3.78; N, 4.78; O, 21.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Aristololactam; Aristolactam I
IUPAC/Chemical Name
Benzo(f)-1,3-benzodioxolo(6,5,4-cd)indol-5(6H)-one, 8-methoxy-
InChi Key
MXOKGWUJNGEKBH-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H11NO4/c1-20-12-4-2-3-8-9(12)5-11-14-10(17(19)18-11)6-13-16(15(8)14)22-7-21-13/h2-6H,7H2,1H3,(H,18,19)
SMILES Code
COc1cccc2c1cc3NC(=O)c4cc5OCOc5c2c34
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 293.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Das A, Kumar GS. Natural Aristolochia Alkaloid Aristololactam-β-D-glucoside: Interaction with Biomacromolecules and Correlation to the Biological Perspectives. Mini Rev Med Chem. 2018;18(12):1022-1034. doi: 10.2174/1389557518666180222170050. PMID: 29473499. 2. Das A, Chatterjee S, Suresh Kumar G. Targeting human telomeric G-quadruplex DNA with antitumour natural alkaloid aristololactam-β-D-glucoside and its comparison with daunomycin. J Mol Recognit. 2017 Oct;30(10). doi: 10.1002/jmr.2639. Epub 2017 May 15. PMID: 28503738.