Diphenan is p-benzyl-phenyl-carbamate. Various workers have reported that diphenan will rid children of oxyurids and it has been claimed to be nontoxic and tasteless and to have the advantage of being a vermicide as opposed to a vermifuge. An attempt has been made to assess the efficacy of diphenan as a vermicide. Diphenan was given far in excess of the normal dosage. Subsequent examnation showed few cures and these mostly in lightly infested children. The condition of many was unchanged and that of some worse after treatment. No toxic reactions were encountered. Moreover, diphenan was found to have no detectable anthelmintic effect when given in high dosage in the treatment of enterobiasis.
MedKoo Cat#: 412384
Name: Diphenan
CAS#: 101-71-3
Chemical Formula: C14H13NO2
Exact Mass: 227.0946
Molecular Weight: 227.26
Elemental Analysis: C, 73.99; H, 5.77; N, 6.16; O, 14.08
The following data is based on the product molecular weight 227.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
