B-3852 | CAS# 117201-47-5 | Bradykinin inhibitor

MedKoo Cat#: 575001 | Name: B-3852

Description:

WARNING: This product is for research use only, not for human or veterinary use.

B-3852 is a Bradykinin inhibitor.

Chemical Structure

B-3852

CAS#117201-47-5

Theoretical Analysis

MedKoo Cat#: 575001

Name: B-3852

CAS#: 117201-47-5

Chemical Formula: C56H74F3N15O13

Exact Mass: 1221.5543

Molecular Weight: 1222.29

Elemental Analysis: C, 55.03; H, 6.10; F, 4.66; N, 17.19; O, 17.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

B-3852; B3852; B 3852

IUPAC/Chemical Name

Arg-pro-hyp-gly-phe-ser-phe-phe-arg-trifluoroacetic acid

InChi Key

VZNNVEYSLFAINP-ZGZDMDBZSA-N

InChi Code

InChI=1S/C55H74F3N15O11/c56-55(57,58)45(77)37(20-11-23-65-54(62)63)68-47(79)39(26-33-15-6-2-7-16-33)69-48(80)40(27-34-17-8-3-9-18-34)70-49(81)41(31-74)71-46(78)38(25-32-13-4-1-5-14-32)67-44(76)29-66-50(82)43-28-35(75)30-73(43)52(84)42-21-12-24-72(42)51(83)36(59)19-10-22-64-53(60)61/h1-9,13-18,35-43,74-75H,10-12,19-31,59H2,(H,66,82)(H,67,76)(H,68,79)(H,69,80)(H,70,81)(H,71,78)(H4,60,61,64)(H4,62,63,65)/t35-,36+,37?,38+,39+,40+,41+,42+,43+/m1/s1

SMILES Code

N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N2C[C@H](O)C[C@H]2C(=O)NCC(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](Cc5ccccc5)C(=O)NC(CCCNC(=N)N)C(=O)C(F)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,222.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Mulinari R, Benetos A, Gavras I, Gavras H. Vascular and sympathoadrenal responses to bradykinin and a bradykinin analogue. Hypertension. 1988 Jun;11(6 Pt 2):754-7. doi: 10.1161/01.hyp.11.6.754. PMID: 2899059. 2. Gavras H, Benetos A, Gavras I. Contribution of bradykinin to maintenance of normal blood pressure. Hypertension. 1987 Jun;9(6 Pt 2):III147-9. doi: 10.1161/01.hyp.9.6_pt_2.iii147. PMID: 3596781.