FAMT | CAS#1270110-75-2 | OAT1 ligand

MedKoo Cat#: 463307 | Name: FAMT

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FAMT is a novel ligand of organic anion transporter OAT1 (SLC22A6), specifically targeting amino acid transporter LAT1 (SLC7A5), exhibiting high renal accumulation.

Chemical Structure

FAMT

CAS#1270110-75-2

Theoretical Analysis

MedKoo Cat#: 463307

Name: FAMT

CAS#: 1270110-75-2

Chemical Formula: C10H12FNO3

Exact Mass: 213.0801

Molecular Weight: 213.21

Elemental Analysis: C, 56.33; H, 5.67; F, 8.91; N, 6.57; O, 22.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

FAMT;

IUPAC/Chemical Name

(S)-2-amino-3-(3-fluoro-4-hydroxyphenyl)-2-methylpropanoic acid

InChi Key

STUMEFJLAPRRME-JTQLQIEISA-N

InChi Code

InChI=1S/C10H12FNO3/c1-10(12,9(14)15)5-6-2-3-8(13)7(11)4-6/h2-4,13H,5,12H2,1H3,(H,14,15)/t10-/m0/s1

SMILES Code

N[C@](CC1=CC=C(O)C(F)=C1)(C)C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 213.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Jin C, Wei L, Ohgaki R, Tominaga H, Xu M, Okuda S, Okanishi H, Kawamoto Y, He X, Nagamori S, Kanai Y. Interaction of halogenated tyrosine/phenylalanine- derivatives with Organic Anion Transporter (OAT) 1 in the renal handling of tumor imaging probes. J Pharmacol Exp Ther. 2020 Sep 27:JPET-AR-2020-000235. doi: 10.1124/jpet.120.000235. Epub ahead of print. PMID: 32981893.