MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 412344 | Name: Carnitine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Carnitine is a quaternary ammonium compound involved in metabolism in most mammals, plants, and some bacteria. In support of energy metabolism, carnitine transports long-chain fatty acids into mitochondria to be oxidized for energy production, and also participates in removing products of metabolism from cells.

Chemical Structure

Carnitine
Carnitine
CAS#406-76-8

Theoretical Analysis

MedKoo Cat#: 412344

Name: Carnitine

CAS#: 406-76-8

Chemical Formula: C7H17NO4

Exact Mass: 179.1158

Molecular Weight: 179.22

Elemental Analysis: C, 46.91; H, 9.56; N, 7.82; O, 35.71

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Carnitine; Carnum; UNIIS7UI8SM58A; UNII S7UI8SM58A; UNII-S7UI8SM58A
IUPAC/Chemical Name
(1)-(3-Carboxy-2-hydroxypropyl)trimethylammonium hydroxide
InChi Key
XQVZUMACGMFEJX-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H15NO3.H2O/c1-8(2)4-3-6(9)5-7(10)11;/h6,9H,3-5H2,1-2H3,(H,10,11);1H2
SMILES Code
C[NH+](C)CCC(O)CC(O)=O.[OH-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 179.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pekala J, Patkowska-Sokoła B, Bodkowski R, Jamroz D, Nowakowski P, Lochyński S, Librowski T. L-carnitine--metabolic functions and meaning in humans life. Curr Drug Metab. 2011 Sep;12(7):667-78. doi: 10.2174/138920011796504536. PMID: 21561431. 2: Rebouche CJ. Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism. Ann N Y Acad Sci. 2004 Nov;1033:30-41. doi: 10.1196/annals.1320.003. PMID: 15591001. 3: Agarwal A, Sengupta P, Durairajanayagam D. Role of L-carnitine in female infertility. Reprod Biol Endocrinol. 2018 Jan 26;16(1):5. doi: 10.1186/s12958-018-0323-4. PMID: 29373970; PMCID: PMC5785901. 4: Borum PR. Carnitine. Annu Rev Nutr. 1983;3:233-59. doi: 10.1146/annurev.nu.03.070183.001313. PMID: 6357236. 5: Bene J, Hadzsiev K, Melegh B. Role of carnitine and its derivatives in the development and management of type 2 diabetes. Nutr Diabetes. 2018 Mar 7;8(1):8. doi: 10.1038/s41387-018-0017-1. PMID: 29549241; PMCID: PMC5856836. 6: Gnoni A, Longo S, Gnoni GV, Giudetti AM. Carnitine in Human Muscle Bioenergetics: Can Carnitine Supplementation Improve Physical Exercise? Molecules. 2020 Jan 1;25(1):182. doi: 10.3390/molecules25010182. PMID: 31906370; PMCID: PMC6982879. 7: Bieber LL. Carnitine. Annu Rev Biochem. 1988;57:261-83. doi: 10.1146/annurev.bi.57.070188.001401. PMID: 3052273. 8: Lv QQ, You C, Zou XB, Deng HZ. Acyl-carnitine, C5DC, and C26 as potential biomarkers for diagnosis of autism spectrum disorder in children. Psychiatry Res. 2018 Sep;267:277-280. doi: 10.1016/j.psychres.2018.06.027. Epub 2018 Jun 14. PMID: 29945069. 9: Suzuki A, Sakai Y, Hashimoto K, Osawa H, Tsuruoka S. Kinetics of carnitine concentration after switching from oral administration to intravenous injection in hemodialysis patients. Ren Fail. 2018 Nov;40(1):196-200. doi: 10.1080/0886022X.2018.1455587. PMID: 29616582; PMCID: PMC6014372. 10: Evans AM, Fornasini G. Pharmacokinetics of L-carnitine. Clin Pharmacokinet. 2003;42(11):941-67. doi: 10.2165/00003088-200342110-00002. PMID: 12908852.